Bibliometric Analysis of Helicobacter pylori Research in Period of 1995 to 2004 Wen-Ta Chiu1, Pei-Fan Hseih2, Hsiao-Ju Cheng2, Yuan-Teng Tseng3 and Yeong-Shan Cheng4 and Yuh-Shan Ho5 1Department of Neurosurgery, Taipei Medical University - Wan-Fang Hospital, Taipei, Taiwan 2School of Public Health, Taipei Medical University, Taipei, Taiwan 3Department of Internal Medicine, Taipei Medical University - Wan-Fang Hospital, Taipei, Taiwan 4Department of Gastroenterology, Taipei Medical University - Wan-Fang Hospital, Taipei, Taiwan 5Bibliometric Centre, Taipei Medical University - Wan-Fang Hospital, Taipei, Taiwan Introduction In 1991, it has been confirmed that gastric lymphoid tissue is known to be acquired in response to local infection by Helicobacter pylori. Barry Marshall and Robin Warren from Australia, are the winners of the Nobel Prize in Physiology or Medicine 2005, “for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease”. Our purpose was to study the H. pylori research performance based on 24,624 documents published in Science Citation Index (SCI)-indexed periodicals between 1995 and 2004. These documents were analyzed and evaluated according to publication distribution and were used to determine the quantitative characteristics of H. pylori research. Methods Documents used in this study were based on the databases of the SCI which was accessed from the ISI Web of Science, Philadelphia, PA, USA. H. pylori and helicobacter pylori were used as keywords to search titles, abstracts, and keywords. Results Of the 12,979 articles in SCI, 7,154 articles had author keyword information. Among 10,122 keywords, 7,089 (70%) keywords were used only 1 time. Table 1. Major characteristics of the research Figure 1. Distribution of author keyword used P: No. of articles AU: No. of authors PG: Total pages NR: Cited reference count SP: single country publications CP: international collaborative publications Table 2. Five most productive corresponding institutes Table 2. Publication activity of top ten countries Conclusions The yearly production has increased with the United States producing 23% the articles followed by Japan with a 15% contribution. Twelve document types were found in the total of 24,624 documents. The five most used author keywords were ‘Helicobacter pylori’, ‘gastritis’, ‘gastric cancer’, ‘duodenal ulcer’, and ‘peptic ulcer’. The G7 industrial countries (U.S.A., Japan, Germany, U.K., France, Italy, and Canada) represent a share of corresponding authors of 64% of world articles. Forty-two percent of all articles were published in journals which listed in the category of gastroenterology & hepatology.