Therapeutics 3: Antibiotics Tutoring By Alaina Darby

Gram Positive and Gram Negative Pathogens Swanson’s Section

The cultured bacteria is purple and grows better without oxygen The cultured bacteria is purple and grows better without oxygen. What is it? Gram positive, aerotolerant Gram positive, microaerophilic Gram negative, obligate anaerobe Gram negative, facultative anaerobe b

Which of the following does not describe a gram positive organism? Inner cytoplasmic membrane LPS in outer membrane Vulnerable to lysozyme Low lipid content b

Where are the penicillin binding proteins located? Outer membrane of gram positive organisms Outer membrane of gram negative organisms Cell wall of gram positive organisms Cytoplasmic membrane of gram positive organisms d

JR has septic arthritis JR has septic arthritis. Which of the following pathogens is the most likely cause? Staph aureus Staph epidermidis Strep viridans Strep pyrogenes a

PBP2A makes s. aureus resistant to which of the following medications? Penicillin Amoxicillin Nafcillin Vancomycin c

JD has a S. aureus infection. It is community acquired JD has a S. aureus infection. It is community acquired. Which of the following would be the first choice? Dicloxacillin Methicillin Ceftaroline Vancomycin a

It turns out that JD’s infection is MRSA. What is not a suitable option? Vancomycin PO Linezolid PO Clindamycin PO Bactrim PO a

The culture from VF’s biopsy his cellulitis comes back with growth of purple chains of spherical bacteria. The bacteria exhibits complete hemolysis. What is the likely pathogen? S. agalactiae S. pyrogenes S. viridans S. pneumoniae b

The culture from VF’s biopsy his cellulitis comes back with growth of purple chains of spherical bacteria. The bacteria exhibits complete hemolysis. How would you treat him if he previously had a rash from PCN exposure? Penicillin Erythromycin PCN + Clindamycin PCN + Gentamicin a

For Which of the following is S. pneumo not the most common cause? Meningitis Otitis media Endocarditis CAP c

Which of the following would be preferred for treatment of meningitis? Cefazolin Cefoxitin Ceftazidime Ceftriaxone d

OK has an enterococcal UTI OK has an enterococcal UTI. Which of the following would be least appropriate? Ampicillin Levofloxacin Vancomycin Nitrofurantoin c

Which of the following would be a PO option for VRE? Linezolid Daptomycin Synercid Bactrim a

Which of the following should never be given in a peripheral line? Linezolid Daptomycin Synercid c

JR is being treated for a Clostridium infection JR is being treated for a Clostridium infection. He presented with diarrhea. His medication includes PCN and a hyperbaric oxygen chamber. Which of the following does he have? Botulinum Difficile Perfringens Tetani c

PR has food poisoning. The bacteria cultures purple and is aerobic PR has food poisoning. The bacteria cultures purple and is aerobic. Which of the following should be suspected? C. botulinium B. cereus L. monocytogenes E. coli b

PR has food poisoning. The bacteria cultures purple and is aerobic PR has food poisoning. The bacteria cultures purple and is aerobic. How should it be treated? PCN Ampicillin Bactrim No treatment is necessary d

PB has septic arthritis and initial cultures are red diplococci PB has septic arthritis and initial cultures are red diplococci. How should it be treated initially? Ceftriaxone Moxifloxacin Penicillin Ampicillin a

Which of the following is not a common gut pathogen? E. coli Klebsiella Pseudomonas Salmonella c

E. coli, proteus, and klebsiella all commonly cause which of the following? Diarrhea Community acquired UTI Noscomial pneumonia Community acquired pneummonia c

JH has bloody diarrhea with elevated WBC’s JH has bloody diarrhea with elevated WBC’s. What would be the most appropriate treatment? Ceftriaxone Ciprofloxacin Ceftolozane Bactrim a

JH has bloody diarrhea with elevated WBC’s JH has bloody diarrhea with elevated WBC’s. What would be the most appropriate to add to ceftriaxone? Imipenem Amoxcillin Gentamicin Levofloxacin c

KT has duodenal ulcers. What bacteria should be most suspected? Campylobacter Shigella H. pylori Salmonella c

Which is least likely to cause bloody diarrhea? Campylobacter V. cholera Shigella E. coli b

FR has a burn would that smells eerily like grapes FR has a burn would that smells eerily like grapes. Cultures show red-colored bacilli. What is the best treatment? Zosyn + gentamicin Zosyn + amikacin Zosyn + tobramycin Zosyn b

Remember the “ABC”s of H. flu! Amoxicillin/Azithromycin Bactrim Clarithromycin/Cephalosporins Type B… blood, brain, bone b

AH checks into the VA medical center and has to be intubated due to pneumonia. The culture is a g(-) rod. He also had confusion and a headache before he was admitted. How should you treat him? Azithromycin + rifampin Ceftriaxone Bactrim Zosyn + gentamicin a