Vibration training intervention to maintain cartilage thickness and serum concentrations of cartilage oligometric matrix protein (COMP) during immobilization

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Vibration training intervention to maintain cartilage thickness and serum concentrations of cartilage oligometric matrix protein (COMP) during immobilization A.-M. Liphardt, A. Mündermann, S. Koo, N. Bäcker, T.P. Andriacchi, J. Zange, J. Mester, M. Heer Osteoarthritis and Cartilage Volume 17, Issue 12, Pages 1598-1603 (December 2009) DOI: 10.1016/j.joca.2009.07.007 Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Three functional weight-bearing regions on each condyle were defined based on flexion angle during normal walking. (a) lateral view, (b) selected cartilage regions of the tibia: regions framed with the grey line were included into the analysis. Osteoarthritis and Cartilage 2009 17, 1598-1603DOI: (10.1016/j.joca.2009.07.007) Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Average changes in serum COMP concentration in response to 6°-HDT bed rest and vibration training (n=8). Serum COMP concentration decreased significantly (P=0.022) after 24h of bed rest and returned to baseline levels after subjects were mobile again (P=0.001). Osteoarthritis and Cartilage 2009 17, 1598-1603DOI: (10.1016/j.joca.2009.07.007) Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions