Integumentary System Chapter 6

Integumentary system Skin and various structures Skin is considered an organ Composed of several tissue types Various functions maintain homeostasis (regulates temp and water loss) protection contains immune cells excretes small amounts of waste

Functions of the integument Protection from: UV light Mechanical damage UV contains a hormone important for T cell growth and development.

Protection from Microorganisms Chemicals

Human skin Epidermis Dermis Subcutaneous layer Outer layer Stratified squamous epithelium Dense irregular connective tissue Adipose tissue Epidermis Outer layer Stratified squamous epithelium Dermis Inner layer Contains collagenous fibers Subcutaneous layer Beneath dermis Adipose tissue

Epidermis Stratified squamous epithelium on basement membrane, cells die as they are pushed up Lacks blood vessels Keratinized- depositing keratin within the cells, toughens, waterproofs Thickest on palms and soles

Psoriasis Cell division gone wrong in the epidermis Excess accumulation of cells

Epidermis Melanocytes produce melanin Melanin absorbs UV radiation Provides skin color

Mutations in melanin genes

https://www.youtube.com/watch?v=BVIIgHyNRdI

Why is tanning so harmful?

Melanoma Squamous cell Basal cell

A B C D -Asymmetry -Border -Color -Diameter http://www.skincancer.org/Media/Default/Page/skin-cancer-information/Melanoma/b.jpg -Diameter

Skin lesions http://www.cs.wright.edu/~agoshtas/paper_fig.html

Possible melanomas Irregular edges Abnormal surfaces Unusual sensation http://nih. cancer.gov

https://www.youtube.com/watch?v=BVIIgHyNRdI 8:12

Dermis Binds epidermis to underlying tissues Dense connective tissue Muscle cells Nerve cells Blood vessels Hair follicles Glands Hair shaft Sweat gland pore Sweat Stratum corneum Stratum basale Dermal papilla Basement membrane Capillary Tactile (Meissner’s) corpuscle Sweat gland duct Sebaceous gland Arrector pili muscle Sweat gland Lamellated (Pacinian) corpuscle Hair follicle Adipose tissue Nerve cell process Blood vessels Muscle layer Sub- cutaneous layer Dermis Epidermis

Accessory structures of the skin Nails Hair Skin glands Receptors

Nails Protective covering Three parts Nail plate Nail bed Lunula

Hair follicles Epidermal cells Tube like depression Root, bulb, shaft (dead) Arrector pili H a i r b u l Dermal blood vessels Hair papilla Region of cell division Eccrine sweat gland Hair follicle Arrector pili muscle Hair root (keratinized cells) Sebaceous gland Pore Hair shaft

Glands Sebaceous Associated with hair follicles Secretes sebum (fatty material) Keeps hair and skin soft and waterproof Acne

Glands Sweat Respond to elevated temps (eccrine), emotional distress (apocrine) Release moisture

Sensory Receptors: Pain Temperature Pressure

The integumentary and homeostasis Prevents heat loss Blood vessels constrict Inactivate sweat glands Prevents overheating Blood vessels dilate Sweat glands secrete (evaporative cooling)

Injury to the integumentary system

Skin repair Inflammation- blood vessels dilate, allow fluids to leak into damaged tissue Fluids have clotting proteins and other substances Increase in WBC, debris removed, clot forms

Cuts A shallow cut, epidermal cells along the cut divide more rapidly than usually Deep cuts, blood vessels break, clotting Growth factors stimulate new tissue formation Excess collagenous fibers may form a scar Scar tissue- strong but not as flexible, can’t perform functions of replaced tissue

Burns First degree Superficial partial-thickness Epidermis Dermal blood vessels dilate Few days to two weeks, no scarring

Burns Second degree Deep partial-thickness Epidermis and some dermis Dermal blood vessels dilate Fluid escapes from capillaries (blisters) Takes longer to heal, may or may not have scarring

Burns Third degree Full-thickness Epidermis, dermis, and accessory structures May or may not heal on own (No photo to reduce gagging in class!!!)

Burns Fourth degree Epidermis, dermis, subcutaneous, connective tissue, bone (No photo to reduce gagging in class!!!)

Burns Healing third degree burns Assists in healing, protects from infection Autograft Allograft Skin substitutes

https://www.youtube.com/watch?v=Dsvtzwp4nG8

Aging of the skin Age spots Epidermis thins Loss of fat Wrinkling, sagging Less sebaceous secretion Decrease in number of hair follicles Slowed melanin production More…

Aging Intrinsic- genetic factors Extrinsic- what we are exposed to (sun, smoking, etc.)

Reversing the aging process Botox- toxin produced by bacterium

Moisturize me!!!

Exam review 50 multiple choice questions 50 questions, 50 minute class = 1 minute per question (be on time!!!) Phones- if they are out at any time, you will receive a zero on your exam. Scantron- bring a #2 pencil. If you are confused about a question, ask me ASAP!!!

Tips Study old quizzes and WODs Several “identify …. in this picture” Pick the best answer (some options may be somewhat correct…you want the best answer) Don’t freak out!