BILL pH Homeostasis

ASTHMA (CAUSES ACIDOSIS) Decreased breathing ↑ CO2 in blood shifts equilibrium will shift to left Increases HCO3– and H+ ions (pH decreases) WHAT WILL ORGANS DO? Kidneys will excrete more HCO3- Respiratory therapy helps remove CO2

REPEATED VOMITING due to illness (ALKALOSIS) Increases HCO3 – and H+ ions (pH decreases) WHAT WILL ORGANS DO? Kidneys will excrete less HCO3- Decreased respiration = less CO2 REMOVED

ANXIETY/HYPERVENTILATION (ALKALOSIS) INCREASED breathing ↓ CO2 in blood shifts equilibrium to right decreases HCO3 – and H+ ions (pH increases) WHAT WILL ORGANS DO? Fainting slows breathing (less CO2 removed) Kidneys will excrete less HCO3-

HEAVY EXERCISE/SEVERE BURNS (CAUSES ACIDOSIS) O2 shortage = more fermentation (reduced blood volume ↓ O2 to tissues) Release of acidic byproducts (lactic acid) ↑ H+ pH ↓ Equilibrium will shift to right WHAT WILL ORGANS DO? Kidneys will excrete MORE HCO3- INCREASED breathing to remove CO2

DIABETES (CAUSES ACIDOSIS) If cells can’t take in glucose for respiration=more fermentation Release of acidic byproducts (lactic acid) ↑ H+ pH ↓ Equilibrium will shift to right WHAT WILL ORGANS DO? Kidneys will excrete MORE HCO3- INCREASED breathing will remove CO2