Assessment of inflammation in noninfectious chronic maxillary sinusitis Pascal Demoly, MDa, Louis Crampette, MDb, Michel Mondain, MDb, Alison M. Campbell,

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Presentation transcript:

Assessment of inflammation in noninfectious chronic maxillary sinusitis Pascal Demoly, MDa, Louis Crampette, MDb, Michel Mondain, MDb, Alison M. Campbell, PhDa, Nadine Lequeuxc, Ingrid Enander, PhDd, Lawrence B. Schwartz, MDe, Bernard Guerrier, MDb, François B. Michel, MDa, Jean Bousquet, MD, PhDa Journal of Allergy and Clinical Immunology Volume 94, Issue 1, Pages 95-108 (July 1994) DOI: 10.1016/0091-6749(94)90076-0 Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 2 Immunohistochemical analysis of ECP (EG1) in a patient with sinusitis and CAR. (Original magnification ×400.) Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 3 Eosinophils (EG1- and EG2-positive cells) in sinus biopsy specimens of patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 4 Immunohistochemical analysis of tryptase (G3) in a patient with sinusitis and CAR. (Original magnification ×400.) Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 5 Mast cells in the submucosa and intraepithelium (G3-positive cells) in patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 5 Mast cells in the submucosa and intraepithelium (G3-positive cells) in patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 6 Neutrophils (elastase), macrophages (CD68), and T cells (CD3) in sinus biopsy specimens of patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 6 Neutrophils (elastase), macrophages (CD68), and T cells (CD3) in sinus biopsy specimens of patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions

FIG. 6 Neutrophils (elastase), macrophages (CD68), and T cells (CD3) in sinus biopsy specimens of patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology 1994 94, 95-108DOI: (10.1016/0091-6749(94)90076-0) Copyright © 1994 Mosby, Inc. Terms and Conditions