Hemostasis Explain the three major steps of Hemostasis. High School pg 349 – 350 College pg 675 – 677 Explain the three major steps of Hemostasis.

Nervous System Exam Data Period Average Highest A B C D F 1st 65.13 107 3 2 6 1 12 2nd 73.24 110 5 4 7 3rd 60.32 16 4th 69.28 106 9 5th 63.85 101 6th 65.67 104 8 10 pt curve

Hemostasis Step 1: Vascular Spasms Figure 10.6, step 1

Hemostasis Injury to lining of vessel exposes collagen fibers; platelets adhere Platelet plug forms Collagen fibers Platelets Step 1: Vascular Spasms Step 2: Platelet Plug Formation Figure 10.6, step 3

Hemostasis Figure 10.6, step 4 Injury to lining of vessel exposes collagen fibers; platelets adhere Platelet plug forms Platelets release chemicals that attract more platelets to the site and make nearby platelets sticky Collagen fibers Platelets PF3 from platelets Calcium and other clotting factors in blood plasma Tissue factor in damaged tissue Step 1: Vascular Spasms Step 2: Platelet Plug Formation + Figure 10.6, step 4

Hemostasis Figure 10.6, step 8 Injury to lining of vessel exposes collagen fibers; platelets adhere Fibrin clot with trapped red blood cells Platelet plug forms Platelets release chemicals that attract more platelets to the site and make nearby platelets sticky Collagen fibers Platelets Fibrin PF3 from platelets Calcium and other clotting factors in blood plasma Formation of prothrombin activator Prothrombin Fibrinogen (soluble) Fibrin (insoluble) Thrombin Tissue factor in damaged tissue Phases of coagulation (clotting cascade) Step 1: Vascular Spasms Step 2: Platelet Plug Formation Step 3: Coagulation + Figure 10.6, step 8

Hemostasis Figure 10.7

Hemostasis Blood usually clots within 3 to 6 minutes The clot remains as endothelium regenerates The clot is broken down after tissue repair

High school pg 359, #31 Answer the following: A middle aged college professor from Boston is in the Swiss Alps studying astronomy. He arrived two days ago and plans to stay the entire year. However, he notices that he is short of breath when he walks up steps and that he tires easily with any physical activity. His symptoms gradually disappear; after two months, he feels fine. Upon returning to the US, he has a complete physical exam and is told that his erythrocyte count is higher than normal. Explain his finding. Will is RBC count remain at this higher-than-normal level? Explain