Ahmed Mohamed Abd Elmajeed 99 Markers Of Pulmoary embolism Under the Supervision of: Prof.Dr Hala Rashad Made by: Ahmed Mohamed Abd Elmajeed 99
Pulmonary embolism (PE) DEF Symptoms Diagnosis Cause
Pulmonary embolism (PE) DEF Symptoms Diagnosis Cause is the blockage of the main artery of the lung or one of its main branches by emboli
Pulmonary embolism (PE) DEF Symptoms Diagnosis Cause DVT Deep vein thrombosis VTE Venous thromboembolism
Pulmonary embolism (PE) DEF Symptoms Diagnosis Cause palpitations difficulty of breathing chest pain on inspiration
Pulmonary embolism (PE) DEF Symptoms Diagnosis Cause Signs symptoms Lab test (D-Dimer ) Imaging CT pulmonary angiography
markers of pulmonary embolism D-dimer fibrin degradation product present in the blood after a blood clot is degraded by fibrinolysis Name? D-dimer concentration help diagnose thrombosis.
D-dimer normally not present in plasma, except when the coagulation system has been activated High sensitivity but low specificity ? negative >>>>>>>rules out thrombosis positive >>>>>>>Thrombosis or other cause
Units µg/mL < 0.5 Nonpregnant adult First trimester 0.05 - 0.95 Second trimester Third trimester µg/mL < 0.5 0.05 - 0.95 0.32 - 1.29 0.13 -1.7
Caoagulation cascade Scaffold of blood clot
False positive readings in Liver disease Malignancy Pregnancy Recent surgery Advanced age
False positive readings in Liver disease Malignancy Pregnancy Recent surgery Advanced age
False positive readings in Liver disease Malignancy Pregnancy Recent surgery Advanced age
False positive readings in Liver disease Malignancy Pregnancy Recent surgery Advanced age
False positive readings in Liver disease Malignancy Pregnancy Recent surgery Advanced age
False negative readings if the sample is taken either too early after thrombus formation or delayed for several days the presence of anti-coagulant because it prevents thrombus extension.
False negative readings if the sample is taken either too early after thrombus formation or delayed for several days the presence of anti-coagulant because it prevents thrombus extension.
1-European heart journal 2008 2-online archive of thrombosis and hemostasis