Chicken infectious anemia

Introduction CIA is infectious disease of young chicken Which is characterized by Aplastic anemia Lymphoid atrophy Any other name of this disease ?

Etiology Chicken infectious anemia virus (CIAV) Genus :Gyrovirus, Family :Circoviridae

Transmission Horizontal transmission.

Vertical transmission Male (Roosters)+ female

Clinical findings . Anorectic, lethargic, depressed, and pale. PCV is low , leukopenia, or pancytopenia. Pale bone marrow.

What this picture is indicating?

Pale anemic organs

S/C Hemorrhages

S/C Hemorrhages/ gangrenous Dermatitis

Postmortem lesions Organs are pale Thymus atrophy Pale or yellow Bone marrow Hemorrhage under the skin, muscle, and other organs.

Hemorrhages on muscles

Thymus atrophy

Thymus atrophy Pale carcass

Pale Bone marrow

Histopathology Depletion of lymphoid cells in lymphoid organs. Hematopoitic cells replaced by adipose tissue & proliferating stroma cells Loss of demarcation between medulla and cortex of bone marrow. Atrophy of Bursal folds

Atrophy of hemopoitic tissue & accumulation of fat cells

Thymus atrophy

Lymphoid depletion & atrophy of Bursal follicles

Diagnosis History Clinical Signs, Gross and Histopathological lesions. PCR ELISA Virus isolation

Prevention : Biosecurity Vaccination of breeders prior to the start of egg production.