Impact of omega-3 polyunsaturated fatty acids on coronary plaque instability: An integrated backscatter intravascular ultrasound study Tetsuya Amano,

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Impact of omega-3 polyunsaturated fatty acids on coronary plaque instability: An integrated backscatter intravascular ultrasound study Tetsuya Amano, Tatsuaki Matsubara, Tadayuki Uetani, Masataka Kato, Bunichi Kato, Tomohiro Yoshida, Ken Harada, Soichiro Kumagai, Ayako Kunimura, Yusaku Shinbo, Katsuhide Kitagawa, Hideki Ishii, Toyoaki Murohara Atherosclerosis Volume 218, Issue 1, Pages 110-116 (September 2011) DOI: 10.1016/j.atherosclerosis.2011.05.030 Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Presence of acute coronary syndrome in patients distributed by their serum levels of omega-3 polyunsaturated fatty acids. ACS was significantly associated with the lower tertile of EPA in A (p<0.001) and of DPA in B (p<0.001). EPA, eicosapentaenoic acid; DPA, docosapentaenoic acid; DHA, docosahexaenoic acid. Atherosclerosis 2011 218, 110-116DOI: (10.1016/j.atherosclerosis.2011.05.030) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Representative images of conventional intravascular ultrasound and integrated backscatter color-coded maps of coronary artery plaques in patients with lipid-rich plaques and those with non lipid-rich plaques. The lipid and fibrous volumes were 63.3% and 35.8% in panel A, and 37.9% and 60.4% in panel B, respectively. Blue, lipid pool; green yellow, fibrous lesion; red, calcified lesion. Atherosclerosis 2011 218, 110-116DOI: (10.1016/j.atherosclerosis.2011.05.030) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions