a powerful alliance for healthy living and active ageing EIT Health: a powerful alliance for healthy living and active ageing Speaker | Location | Date

Innovation in Europe Most EU research funding & support is provided for early Technology Readiness Levels (TLR) 1-5 gap in funding for projects > TLR 6-9 lack of ‘entrepreneur education’ The EIT was founded to develop solutions for rapidly emerging societal problems products that meet the needs and desires of consumers EIT Health ensures the connection of education, research and business (knowledge triangle) strengthens entrepreneurial education and support supports innovative ideas and transformational business projects

Our mission: EIT Health promotes entrepreneurship and innovates in healthy living and active ageing, with the aim to improve quality of life and healthcare across Europe. EIT Health aims to accelerate entrepreneurship and innovation in healthy living and active ageing, providing Europe´s top talents with new opportunities and resources for the benefit of all citizens. The focus is to: offer answers to future challenges of healthcare strengthening the European healthcare industry supporting people in maintaining and managing their health

Europe‘s healthcare challenges Societal changes Ageing population Downward trend in birth rates Increasing life expectancy by approx. 4-5 years per generation Leading to A wider gap between active and inactive people, reducing the population within the labour force A larger number of older people in long-term care, e.g. due to cardiovascular disorders, diabetes or functional loss A dramatic increase in expenditures for health and social care

Healthcare expenditure by age Shares of healthcare expenditure by age in total healthcare expenditure Source: Maisonneuve, C., and J. Martins. 2013. „Public Spending on Health and Long Term Care: A New Set of Projections.“ OECD Economic Policy Paper No. 6. Paris: OECD.

How healthcare costs are rising Projected public health and long-term care expenditure in the OECD countries as a % of GDP, in 2060 Source: Maisonneuve, C., and J. Martins. 2013. „Public Spending on Health and Long Term Care: A New Set of Projections.“ OECD Economic Policy Paper No. 6. Paris: OECD. 1 The cost-containment scenario assumes that policies act more strongly than in the past to rein in some of the expenditure growth. 2 The cost-pressure scenario assumes no stepped-up policy action. We see an average of GDP rising from 6% in 2011 to 9.5% in 2060 in the cost containment scenario and 14% in the cost pressure scenario Examples of cost drivers are: - Increase of chronic diseases - Dementia - Functional loss - co-morbidity

Scenarios for rising healthcare costs in CLC countries Projection scenarios for public healthcare spending In billions of Euros Average 2006-2010 Cost-containment Scenario 2060 Cost-pressure scenario 2060 Belgium 23,237 30,850 46,475 Denmark 16,238 21,393 31,446 France 157,801 204,715 287,881 Germany 212,842 279,902 393,613 Ireland 10,398 15,124 22,496 Netherlands 42,417 58,324 84,172 Spain 58,305 88,499 128,063 Sweden 28,422 37,035 53,399 United Kingdom 146,465 191,531 279,411 Note: These figures are based on projection scenarios for public healthcare spending in % of GDP conducted by the OECD, calculated with GDP figures of the Eurostat GDP ranking 2014. Sources: Maisonneuve, C., and J. Martins. 2013. „Public Spending on Health and Long Term Care: A New Set of Projections.“ OECD Economic Policy Paper No. 6. Paris: OECD. "Eurostat – Tables, Graphs and Maps Interface (TGM) table". Epp.eurostat.ec.europa.eu. Retrieved 9 November 2015.

Connecting high potential areas with integrated innovation processes Promote Healthy Living Enable people to take charge of their own health Lifestyle intervention Self-management of health Support Active Ageing Workplace interventions Overcoming functional loss Optimise the physical working environment Improve Healthcare Improving healthcare systems Treating and managing chronic diseases Establish holistic care solutions in home and clinical settings Our activities fall within our three strategic challenges including the need to address barriers to improving healthcare. These form the backbone of our activities. Business Objectives Examples

A paradigm shift is needed Professional inertia Professional-centric Surrender Formal Institutional care Expert opinion I am entitled to health care Empowerment Citizen-centric Actively involved Individual norms Own-control Own values and norms I am supported in managing my own health What is the matter with you? What matters to you? What is the fundamental problem we are addressing? -> It is the need to accelerate the paradigm shift that is moving from professional to patient-centric. So instead of asking the question: What is the matter with you?, we should ask: What matters to you? Our portfolio focuses on empowerment and supporting citizen to manage their own health.

Many achievements in 2015 Formally established the KIC LE on time Built a strong portfolio of activities Set-up of all CLCs and InnoStars concluded by end of 2015 Selected 23 Innovation Projects Prepared the launch of Accelerator Developed the Campus portfolio following the Stellar approach Launched branding and communication activities Hired management team Carried out first activities (Summer School) Developed our relationship with the EC and the EIT

Deliver tangible results Develop our organisation Our ambitions for 2016 19 new products 70 business ideas incubated 700 health professionals trained > 150,000 participants in EIT Health MOOCs Deliver tangible results Build connections Linkages between Campus, Accelerator and Projects Users/patients in innovation activities Payers to engage in EIT Health Communication: external/internal Develop our organisation Strengthening the partnership Establish a strategic process for 2017 Business Plan Strategic portfolio of transformational innovation Grow capabilities and double portfolio size in 2017 Against this background, our ambition is to make EIT health a key driver in connecting partners in health initiatives in Europe, driving strategic issues and delivering tangible results already in 2016 (details see dark blue box). We will do that by establishing close linkages between all activities and partners involved (see light blue box). Of course, we also plan to develop our organisation further (see green box).

EIT Health: leveraging the potential invests in Europe’s best entrepreneurial talents and creative minds fosters the development and commercialisation of smart product and service solutions One of the largest healthcare initiatives worldwide with more than 130 leading organisations, covering all areas of healthcare. Industry Public University Research How do we do it? -> By leveraging the full potential of being one of the largest healthcare initiatives worldwide. In numbers, this means EIT Health has more than 130 leading member organistions from all important healthcare areas, namely industry, public, research and higher eductation. By investing in Europe‘s best entrepreneurial talents and creative minds, EIT Health fosters the development and commercialisation of smart product and service solutions.

European reach International Headquarter at TU Munich 6 Co-Location Centres (CLCs): UK/Ireland (London) Scandinavia (Stockholm) Belgium/Netherlands (Rotterdam) Germany (Mannheim/Heidelberg) France (Paris) Spain (Barcelona) 8 InnoStars regions in 6 countries: Croatia Hungary Poland Portugal Slovenia Wales Co-location centres InnoStars regions International HQ

Interim CLC Director Belgium/Netherlands A strong partnership across Europe CLC UK/Ireland CLC Scandinavia CLC Belgium/Netherlands We have a strong partnership all along the knowledge triangle of committed, experienced and highly competent partners in academia, industry (Pharma, medtech, ICT, large and small), research centres, testing labs, incubators and accelerators etc. CLC Germany CLC Spain CLC France InnoStars Menno Kok Interim CLC Director Belgium/Netherlands

InnoStars: emerging innovation hubs Leveraging the potential across Europe for inclusive growth West Wales & Valleys (UK) West Slovenia (SL) Continental Croatia (HR) Lodzkie (PL) Lisbon / Centro Region (PT) North Great Plain / Central Hungary (HU) EU The green arrow on the previous slide showed that EIT Health is also acitve in other regions accross Europe, where we see high potential for inclusion and inclusive growth -> the InnoStars. InnoSTARS is a Consortium of EIT Health Associated Partners linked to “Convergence Regions” or to “Regions from Countries eligible for H2020 Widespread Programs” (below 70% of the EU27 RDI index average of composite indicator). They offer the EIT Health consortia: 1) innovation potential;  2) new talents from young students and entrepreneurs;  3) test bed environments and market opportunities for EIT Health partners By including them into the EIT Health consortia, two requests of EIT were solved: a) KICs should not overlook the talent and idea potential of the periphery b) Less developed regions should benefit from the innovations of the more developed regions

Regions in Croatia, Hungary, Poland, Portugal, Slovenia and Wales How EIT Health is organised EIT EIT Health CLCs EIT Health LE Management Board IP Board Supervisory Board Partner Assembly ELSI Belgium/Netherlands France Germany Scandinavia Spain UK/Ireland InnoStars Regions in Croatia, Hungary, Poland, Portugal, Slovenia and Wales Core Partner interacts So how does EIT Health manage to deal with all the different members, regions and stakeholders? We ensure a close and good interaction with The EIT The management team The supervisory board The CLCs and Of course, with our partners Legal entity and headquarter of EIT Health e.V. established at TU Munich CEO appointed as of 1 September: Sylvie Bove Supervisory Board active CLC colocations established, managing directors hired, portfolios assembled

Non-EIT Funding (min 75%) Leveraging and pooling resources EIT Funding (max 25%) Non-EIT Funding (min 75%) Total KIC Funding (100%) This is how we get the resources for our activities (depending on audience, budget might or might not be stated) Membership fees: Core partner: 75,000 EUR p.a. Associate partner: 25,000 EUR p.a.

Director School of Medicine, Imperial College London Imperial College: partner of EIT Health Prof. Elio Riboli Director School of Medicine, Imperial College London THIS IS AN EXAMPLE (quote taken from EIT Health image video matrial) and can be individually adapted by each member for own presentations!!! So why are we partner of EIT Health? … individual explanation … and we fully believe that EIT Health will be able to turn ideas into economic success by integrating innovation, education and entrepreneurship. “EIT Health covers the whole spectrum from basic research to the translation of this knowledge into products and services, which eventually will become available to the general public and patients.”

Integrating innovation, education and entrepreneurship Cross-linkages - CAMPUS provides education to turn business ideas within PROJECTS into practice. - PROJECTS identify innovative ideas and put them into practice. They are backed by ACCELERATOR, assisting with private equity access and providing living labs and test beds across Europe. - ACCELERATOR offers support for CAMPUS to foster students’ project ideas (e.g. by business coaches).

EIT Health Innovation PROJECTS Projects by Ideas Projects by Design Focus on innovation: Developing achievable products and services Including educational elements of EIT Health CAMPUS Focusing on activities with a clear added value for all healthcare challenges defined by EIT Health Investing in Projects by Design and Projects by Ideas

> live longer and healthier Innovation Project example Aim: improve ‘quality’ of years to be lived > live longer and healthier FACET FACET = Integrated supportive services/products to promote FrAilty Care and wEll funcTion FACET focuses on the quality of the years lived through a transversal and holistic approach for managing of frailty. The development of early detection tools will permit intervention to prevent or delay the onset of frailty and prevent further disability. FACET will impact on the quality of life of 13.05 million people with a potential of prevention in near half a million citizens annually. Strategy focuses on the ‘quality’ of years to be lived: liver longer AND healthier The aim is to promote independence of older adults, functional ability / mobility and the self management of health for the older population FACET will support other EIT Health example areas such as Motivate Active Personal lifestyles and sustainable Continuum of care to support active living in Europe as well as cross challenges Early detection of impeding disease Solution: algorithm and clinical friendly tools for frailty detection / and/or disability Deliverables / Innovation Plateform integrating existing services with new data acquisistion services, data analytics, algorithms) , 4-5 news or improved product services processes launched Business generation (together with Business pillar) Personalized services for people and services for the professional environment (preventive and interventional: nutritional, medication, physical and cognitive intervention 55+y)v and those who are in the current workforce and those who are retired 6 to 7 new business ideas incubated Education (together with education pillar) 6 new courses addressed to a wide audinece (including 1 MOOC on Frailty) 15 new graduates and 5 master degress and at least 375 health care professional trained Communication 20 to 25 events with an average audience of 100 people per event Research and investigation Activity to improve current products and services to approach frailty 9 Partners: 4 Industry 4 Research 1 SME (InnoStar) 3 countries Spain, Wales, France Predicted achievements: positive impact on quality of life of 13 million people in Europe

EIT Health CAMPUS Focus on education: Summer Schools and Graduate Hubs Professional and Executive Education Flagship Initiatives MOOCs and Digital Engagement Focus on education: Improving educational modules for healthcare innovation Increasing innovation skills and fostering entrepreneurial spirit amongst students Conveying a better understanding of patients’ needs in personalised care among healthcare professionals and executives Providing new competencies to the public and private sector on how to adapt the workplace to an ageing population Teaching novel processes and best practices for patient-centred care and self-management

Campus: education of professionals and executives is a key education component Create sustainable and innovative workplace Develop patient-centred and personalised healthcare Engage professional citizens for healthy living and active ageing Enable executives to realise the full potential of innovations Aim: citizen-centred active ageing and well-being EIT Health is the only initiative that can make a paradigm shift by reaching the executives. While it is good to train students and lower doctors in these innovation techniques and ideas, you often hit a brick wall of professional defensiveness and organizational rigidity. The only way to deal with this is to CHANGE THE LEADERS AND ORGANZIATION by helping the leaders understand the citizen-centric approach.

EIT Health ACCELERATOR Innovation Training and Support Market Preparation and Expansion User Ideation and Validation Focus on business creation: Supporting start-ups, spin-offs and business ideas in the healthcare/life science sector Accelerating research, products and services through easier access to EIT Health Living Labs and Test Beds Improving time-to-market for new services and product launches Providing market knowledge and capabilities for market access Launching Proof-of-Concept and SME-driven Head Start Projects

Accelerating growth living labs and test beds Business Plan competition / entrepreneurship training Funding of head start project Embedded coaching As an example for EIT Health Accelerator, the two ‘Go Global’ programmes help small SMEs grow by training them in how to export their products and services to new markets. For instance, with our living labs, we have ‘real life’ living environments at a number of CLCs such as Scandinavia, France and Spain. These are apartments or houses where ‘end users’ can be housed and can interact with many sorts of innovations, providing critical feedback to the innovators. These could be IT innovations that help elderly citizens interact with local services and other innovations supporting independent living. By funding headstart projects, the CLCs will support, for instance, very small companies with an ‘almost-ready’ product by testing it in a suitable LL/TB facility, or by supporting the project teams with key expertise – for example to help them gain knowledge of local regulatory and procurement procedures in a key market of which the team has no knowledge. Another example could be the use of the fund to develop a prototype device to both test and show to potential investors. Access to living labs and test beds Link with investor community Support market access and launch

InnoStars partners strategically placed in RIS areas RIS – new ideas and talents from the periphery RIS activities through InnoStars CLCs InnoStars RIS regions RIS + local funding, community building, project management Innostars partners are located in the RIS-eligible regions. Thus our RIS activities will be organised by locally embedded Innostars partners. Business Plan Competitions and Recruitment Roadshows will select the best startups and the best talents. After a matchmaking (matching RIS startups and talents with the needs of EIT Health partners) they will be offered European opportunities (market and education/training respectively) through EIT Health partners. After the program they will return to their home country (EIT request) and create jobs. With the successful participants we will be able to leverage ESIF and we will be able to strengthen Innostars networks. Stronger networks will drive better and better RIS activities year by year. Motivation, selection, training, application Best talents Best start ups Campus Accelerator Alumni Export ＆ job creation Projects InnoStars partners strategically placed in RIS areas

European synergies for health With our goal of creating impact and a paradigm shift, this is what EIT Health brings to the table: A strong network of competent and experiences health providers (Pharma, medtech, small and large companies) Europe’s strongest academic partners with a wealth of knowledge in healthcare Living labs and business accelerators that are considered some of the best worldwide ( Uppsala, Delft, etc) A keen understanding of the whole value chain

EIT Health – a powerful alliance EIT matters EIT Health matters Health matters Our vision: Shaping future healthcare for the benefit of our citizens by Integrating technology, patients and professionals Accelerating the development of future health solutions And their implementation

Thank you! https://twitter.com/eithealth www.facebook.com/eithealth www.linkedin.com/company/eithealth

EIT Health Nu går (startar) tåget….. Back up

The EIT Health Management team Sylvie Bove CEO Katharina Ladewig CLC Director UK/Ireland Jan-Philipp Beck COO Armin Pscherer CLC Director Germany Menno Kok Interim CLC Director Belgium/Netherlands Stefan Halwax CFO Palle Høy Jakobsen CLC Director Scandinavia Ursula Mühle Director Education Menno Kok CLC Director Belgium/Netherlands Kurt Höller Director Business Creation Andy Browning Director Innovation Balázs Fürjes Director InnoStars Marco Pugliese CLC Director Spain Jason Théodosiou CLC Director France Headquarter Munich InnoStars regions Co-location centres

The EIT Health Supervisory Board

Competitive selection process EIT Health Innovation portfolio I. Setting strategic focus II. Cross-area ideation facilitated by CLCs III. Call process and project development IV. External evaluation and EIT Health hearings V. Portfolio building VI. Final review with focus on cross-linkages

The EIT: spurring innovation and entrepreneurship across Europe

EIT – European Institute of Innovation and Technology Created in 2008, The EIT is an EU body that enhances Europe’s ability to innovate by nurturing young entrepreneurial talent and supporting new ideas through the Knowledge and Innovation Communities (KICs). The EIT brings together the three sides of the “knowledge triangle”: business, higher education institutions and research centres. Created in 2008, the EIT’s mission is to: increase European sustainable growth and competitiveness; reinforce the innovation capacity of the EU Member States; and create the entrepreneurs of tomorrow and prepare for the next innovative breakthroughs. The EIT creates an unprecedented level of collaboration between innovation and excellence centres with the aim of boosting the innovation process: from idea to product; from lab to market; and from student to entrepreneur. The EIT is the first EU initiative to fully integrate all three sides of the Knowledge Triangle (higher education, research and business) by way of so-called Knowledge and Innovation Communities (KICs). The integration of all three sides and the effective transmission and sharing of knowledge, information and skills for joint exploitation is crucial to delivering the jobs and growth opportunities that Europe is seeking, as excellent researchers, students and entrepreneurs working in isolation are much less efficient in delivering the results needed and wanted by the market and consumers. By connecting European business and research, businesses stand to gain as they will be given fresh opportunities to commercialise the most up-to-date and relevant research findings, with the aim of giving Europe first-mover advantage in the latest technological and non-technological fields as well as in open innovation. In return, research organisations will benefit from additional resources, an enhanced networking capacity, and new research perspectives stressing interdisciplinary approaches in areas with strong societal and economic importance. By adding higher education into the mix, businesses will be able to take advantage of a workforce with skills tailored to their needs able to drive their market share forwards; and students will benefit from an education that will make them more attractive to future employers and also more apt at contributing to the development of those employers’ businesses. from idea to product from lab to market from student to entrepreneur

The EIT innovation model Outreach Dissemination GROWTH INNOVATION CAPABILITIES JOBS Business creation activities Higher education activities Innovation-driven research activities Research actors Higher education Entrepreneurship Entrepreneurial talent Start-ups, Spin-offs New products, services and business models

The EIT’s KIC model Knowledge and Innovation Communities (KICs) Highly integrated, creative and autonomous partnerships Developed to foster innovative products, services and new business Driven by a pursuit of excellence Encourage growth and nurture young entrepreneurial talent Characterised by a long-term perspective KIC annual total budget: €50-300 million ‘Other’ funding from a variety of sources: National/regional EU (non-EIT) e.g. FP7 research grant or structural funds Private funding Own resources

The EIT‘s first KICs addressing climate change mitigation and adaptation addressing sustainable energy addressing information and communication technologies

New and upcoming KICs Since 2014 adressing sustainable exploration, extraction, processing, recycling and substitution addressing healthy living and active ageing Upcoming KICs: Food4Future (2016) Added Value Manufacturing (2016) Urban Mobility (2018)