Incidence of Late Rectal and Urinary Toxicities After Three-Dimensional Conformal Radiotherapy and Intensity-Modulated Radiotherapy for Localized Prostate.

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Incidence of Late Rectal and Urinary Toxicities After Three-Dimensional Conformal Radiotherapy and Intensity-Modulated Radiotherapy for Localized Prostate Cancer Michael J. Zelefsky, M.D., Emily J. Levin, B.A., Margie Hunt, M.S., Yoshiya Yamada, M.D., Alison M. Shippy, B.A., Andrew Jackson, Ph.D., Howard I. Amols, Ph.D. International Journal of Radiation Oncology • Biology • Physics Volume 70, Issue 4, Pages 1124-1129 (March 2008) DOI: 10.1016/j.ijrobp.2007.11.044 Copyright © 2008 Elsevier Inc. Terms and Conditions

Fig. 1 The incidence of late Grade ≥2 rectal toxicities by prescription dose. International Journal of Radiation Oncology • Biology • Physics 2008 70, 1124-1129DOI: (10.1016/j.ijrobp.2007.11.044) Copyright © 2008 Elsevier Inc. Terms and Conditions

Fig. 2 The incidence of late rectal toxicities (Grade ≥2) correlated by the presence of an acute symptom (Grade ≥2). GI = gastrointestinal. International Journal of Radiation Oncology • Biology • Physics 2008 70, 1124-1129DOI: (10.1016/j.ijrobp.2007.11.044) Copyright © 2008 Elsevier Inc. Terms and Conditions

Fig. 3 The incidence of late Grade ≥2 urinary toxicities by prescription dose. A significant increase in Grade 2 toxicities was observed for patients treated to 81 Gy compared with lower doses (p = 0.01). International Journal of Radiation Oncology • Biology • Physics 2008 70, 1124-1129DOI: (10.1016/j.ijrobp.2007.11.044) Copyright © 2008 Elsevier Inc. Terms and Conditions

Fig. 4 The incidence of late urinary toxicities (Grade ≥2) correlated by the presence of an acute symptom (Grade ≥2). GU = genitourinary. International Journal of Radiation Oncology • Biology • Physics 2008 70, 1124-1129DOI: (10.1016/j.ijrobp.2007.11.044) Copyright © 2008 Elsevier Inc. Terms and Conditions