Update on the Regional NHS Genomic Medicine Centres HEE South West Annual Stakeholder event Taunton Marie Taylor SWGMC and Mel Watson WEGMC 1st March 2017

Update What is Genomics? The 100 000 Genome Project Genomics Education Programme (HEE) and National progress Local activity – South West and West of England

Study of Whole Genome and how it works Includes the technologies and interpretation Slide courtesy of NHS England

Includes Cancer and Rare Diseases

100,000 Whole Genome Sequences with linked data set by end 2017 100 000 Genome Project Aims & Objectives 10 Dec 2012: David Cameron announces that the Government intends to achieve a paradigm shift in the way that genomics are used across the NHS and commits the UK to sequencing 100,000 whole human genomes from patients with rare/inherited diseases and certain common cancers by the end of 2017 100,000 Whole Genome Sequences with linked data set by end 2017 Increased discovery of pathogenic variants leading to new treatments, devices and diagnostics Accelerate uptake with advanced genomic medicine practice integrated into the NHS Increase public understanding and support for genomic medicine Stimulate and advance UK life sciences industry and commercial activity in genomics

Genomics Education Programme

NHS Genomic Medicine Centres NHS Genomic Medicine Centres (NHS GMCs) : mapped against AHSN boundaries NHS GMCs work in partnership with academia, patients and industry through the AHSNs 

To ensure that the health and care workforce of today and tomorrow has the right numbers, skills, values and behaviours to harness the potential of genomic medicine through the mainstream adoption & use of genomic technologies & practice

HEE Genomics Education Programme Strategy and Aims Embed genomics into education: upskilling current & future healthcare workforce Whole-genome sequencing (WGS) & functional genomics integrated into mainstream care - benefit patients & the public Build capacity & capability – addressing prospective needs with a world- leading response to the genomic medicine revolution Building upon previous workforce investment in the scientific workforce and genetics Ensuring legacy of the 100,000 Genomes Project is embedded in the healthcare system & wider economic contribution Key question Slide courtesy of Dr Anneke Seller

Interventions to support workforce transformation at all levels and across all settings Highly Specialised workforce clinical and laboratory genetics, molecular pathology, molecular haematology, bioinformatics Specialist clinical workforce Eg cancer surgery & medicine, cardiovascular, diabetes, neurology and other specialist teams Broader clinical workforce general practice, all healthcare professionals Non-clinical workforce & society including managers & commissioners, patients and public Specialist curricula, workforce capacity, targeted training Broader-based training & education Access education, just-in-time resources, awareness raising For workforce transformation to be effective we need to reach the full workforce. We also need to make sure our resources are appropriate to the different areas of the workforce. We are therefore aligning our work to this pyramid structure

Genomics knowledge into action Incorporating relevant genomic medicine at all stages of the education continuum The GEP continuum of genomic medicine education Genomics knowledge into action Core genomics concepts Real clinical examples to introduce major concepts; explain relevance to patient care Contextualising the genomics concepts Expand appropriate underlying concepts, tailored for specialty/role Genomics in clinical practice Competences appropriate to role undertaken; ‘as required’ information *Pre-registration Post-registration Workplace *This also covers the training undertaken by non-registered NHS staff e.g. Nursing Associates

Highlights and Exemplars – Jan 2017 The Consent Conversation Preliminary evaluation Self rated: After completing the course 95%* felt they had an appropriate level of knowledge to take consent (self-rated). 92%* felt ready to take consent * n=168 Future Learn – MOOC ‘’This course has taught me a lot and helped to secure a lot of the terms and processes in my head by putting them into context –something which is not possible to achieve just by reading scientific papers’’

Genomic Champions spreading the word Training and Learning Logs submitted each month

Awareness Raising and Training 2016 Exome Sequencing day Rare Disease Consent Training Session Cancer Launch Day Training Needs Assessment 2017 Webinar for clinical teams (cancer) Consent Training Session (cancer) Webinar for pathology (cancer) Exome Sequencing day Cancer Research UK event for SW GPs Exome Sequencing day, September 2016 – attended by 74 delegates Cancer Launch Day, November 2016 – attended by 70 people Cancer Consent Training day, 21st February 2017 – bookings being taken SW Webinar for Clinical teams (Cancer) 23rd February SW Webinar Pathology (Cancer) 2nd March Exome Sequencing day, March 2017 – fully booked TNA - 107 responses (81 from SW GMC area ) Cancer Research UK Evening for GPs in the SW – 14th March 2017

Education and Training HEE Funding 51 Full/PT Students Diploma 22 PG Cert 26 CPD Plus 7 self funding Students Students attending the Counselling Course

September intake place of work (HEE funded)

West of England Genomics Medicine Centre – our geography

Clinical engagement and networking Clinical engagement activity snapshot Oct- Dec 2016 34 engagement events >1000 audience members Presentations at National Conferences Roadshows at LDPs Grand Rounds at local providers Laboratory staff updates Lectures to local students Multidisciplinary clinical teams Targeted Informatics training Targeted consent training Co-delivery Rare & Common Disorders Module University of Exeter & UWE (Feb 2017). Cancer Module March 2017

Genomic Champions

Workforce Development –Achievements in Q3 ‘Box-Ed’ targeted engagement with schools progressed to pilot stage (UWE & HEE funded) @Bristol plans to develop community engagement package Competency framework and Targeted training packages in development Informatics Consenting Training needs analysis disseminated – closed 28th February

Patient Public involvement Attend rare disease and cancer clinical oversight groups Support to ‘get genomics on the agenda’ of public meetings Contribution to pathway review meetings

The workforce Transformation in Medicine – requires Transformation in workforce Multi-professional and patient perspective Strengthening the nursing and midwifery contribution to the genomes work Primary Care Healthcare Science Training framework Cross organisational boundaries A Commissioned service – competent workforce The legacy?

Further Information http://swgmc.org/ http://www.wegmc.org/ https://www.genomicseducation.hee.nhs.uk/ https://www.genomicsengland.co.uk/