LINKS BETWEEN DRUG METABOLISM AND

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LINKS BETWEEN DRUG METABOLISM AND Innovate Pharma 2017 PERTH LINKS BETWEEN DRUG METABOLISM AND INSULIN RESISTANCE IN GLOBAL COMMUNITIES Prof. Ian Martins INTERNATIONAL SUMMIT ON PHARMA AND CLINICAL TRIALS SYDNEY, AUSTRALIA *Centre of Excellence for Alzheimer's Disease Research and Care, EDITH COWAN UNIVERSITY School of Psychiatry and Clinical Neurosciences, University of Western Australia, Sir James McCusker Alzheimer's Disease Research Foundation, Hollywood Private Hospital, Perth, WA, Australia.

BACTERIAL LIPOPOLYSACCHARIDE DIABETES EBOOK: Nutritional diets accelerate amyloid beta metabolism and prevent the induction of chronic diseases and Alzheimer’s disease. Photon ebooks. 2015.50 READS. Jan 11th 2017. ARTICLE: Diet and Nutrition reverse Type 3 Diabetes and Accelerated Aging linked to Global chronic diseases. J Diab Res Ther. 2016; 2(2). 300 READS, Feb 28th. ARTICLE: Diabetes and Organ Dysfunction in the Developing and Developed. World Global Journal of Medical Research: 2015. 10 CITATIONS. OCT 5TH. 2016. ARTICLE: Links between Insulin Resistance, Lipoprotein Metabolism and Amyloidosis in Alzheimer’s Disease. Health. 2014. March 29th 2017. 20 READS. ARTICLE: Caffeine consumption with Relevance to Type 3 diabetes and accelerated brain aging. Research and Reveiws: Neuroscience. 2016. Apr 19th 2017. 100 READS ANTI-AGING GENES EC Nutrition Editor’s Column – 2017 Heat Shock Gene Dysregulation and Inactivation of Drug Therapy”. EC Pharmacology and Toxicology ECO.01 (2017): 13-15. Calorie Sensitive Anti-Aging Gene Regulates Hepatic Amyloid Beta Clearance in Diabetes and Neurodegenerative Diseases”. EC Nutrition ECO.01 (2017): 30-32 ARTICLE: Heat shock gene Sirtuin 1 regulates post-prandial lipid metabolism with relevance to nutrition and appetite regulation in diabetes. International Journal of Diabetes and Clinical Diagnosis. Int J Diab Clin Diagn. 2016, Dec 13th, 50 READS ARTILCE: Anti-Aging Genes Improve Appetite Regulation and Reverse Cell Senescence and Apoptosis in Global Populations. AAR, 2016, Nov 24th, 50 READS, 10 CITATIONS. ARTICLE: Unhealthy Nutrigenomic Diets Accelerate NAFLD and Adiposity in Global communities. J Mol Genet Med. 2015. 2017 50 READS/10 CITATIONS. EBOOK. Nutrition increases Survival and Reverses NAFLD and Alzheimer's disease LAP LAMBERT.2015.2017 May 7th 20 READS. DRUG METABOLISM CHAPTER: Nutritional and Genotoxic Stress Contributes to Diabetes and Neurodegenerative Diseases such as Parkinson's and Alzheimer's Diseases. - Frontiers in Clinical Drug Research -CNS and Neurological Disorders. Volume 3 Editor: Atta-ur-Rahman 2015. 158-192 (35). March 29th. 20 READS. ARTICLE: Drug Therapy for Obesity with Anti-Aging Genes Modification. Ann Obes Disord. 2016; 1(1): 1001. ARTICLE: Drug-Drug Interactions with Relevance to Drug Induced Mitochondrial Toxicity and Accelerated Global Chronic Diseases. EC Pharmacology and Toxicology 3.1 (2017): ARTICLE: Early diagnosis of neuron mitochondrial dysfunction may reverse global metabolic and neurodegenerative disease. Global Journal of Medical Research.. 2016;2: 1-8. ARTICLE: Magnesium Therapy Prevents Senescence with the Reversal of Diabetes and Alzheimer’s Disease. Health, 2016. Jan 16th 2017. 50 READS. BACTERIAL LIPOPOLYSACCHARIDE ARTICLE: Food intake and caffeine determine amyloid beta metabolism with relevance to mitophagy in brain aging and chronic disease. EJFST.2016;DEC 13TH, 20 READS. ARTICLE: Bacterial Lipopolysaccharides Change Membrane Fluidity with Relevance to Phospholipid and Amyloid Beta Dynamics in Alzheimer’s Disease. J Microb Biochem Technol, 2016, NOV 18th ,50 READS. ARTICLE: Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases. Int J Mol Sci.SEP 14th, 20 READS, 10 CITATIONS.

CALORIE SENSITIVE SIRTUIN 1 CALORIE SENSITIVE SIRTUIN 1

Albumin-drug interaction and its clinical implication. Biochim Biophys Acta. 2013 Dec;1830(12):5435-43. Albumin-drug interaction and its clinical implication. Yamasaki K1, et al. Faculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Kumamoto 860-0082, Japan. Abstract Human serum albumin acts as a reservoir and transport protein for endogenous ( e.g. fatty acids or bilirubin) and exogenous compounds (e.g. drugs or nutrients) in the blood. The binding of a drug to albumin is a major determinant of its pharmacokinetic and pharmacodynamic profile.Drug-albumin interactions appear to predominantly occur at one or two specific binding sites. The nature of these drug binding sites has been fundamentally investigated as to location, size, charge, hydrophobicity or changes that can occur under conditions such as the content of the endogenous substances in question. Such findings can be useful tools for the analysis of drug-drug interactions or protein binding in diseased states. .