Vladimir S. Fonov, Mahsa Dadar, Xiao Yiming, D. Louis Collins 

Slides:



Advertisements
Similar presentations
2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.
Advertisements

Sleep disruption changes across the disease trajectory: Pilot findings from the healthy patterns sleep study Nancy A. Hodgson, Albert J. Safi Alzheimer's.
Capillary dysfunction in Alzheimer's disease
DIAGNOSTIC ACCURACY AND CONFIDENCE IN THE CLINICAL DETECTION OF COGNITIVE IMPAIRMENT IN EARLY-STAGE PARKINSON’S DISEASE  Kathryn A. Wyman-Chick, Phillip.
Relationship between Microstructural Degeneration of the Corpus Callosum, White Matter Hyperintensities, and Motor Function in Cognitively Intact Elderly 
Hilkka Liedes, Jyrki Lötjönen, Gerald P. Novak, Mark Forrest Gordon 
Comparison of accelerated and nonaccelerated MRI in ADNI: Effects on measures of brain and ventricular volumes and rates of atrophy  Kelvin Leung, Casper.
A SYSTEMATIC REVIEW AND META-ANALYSIS COMPARING QUALITY-OF-LIFE RATINGS FROM FAMILY AND PAID CAREGIVERS OF PEOPLE WITH DEMENTIA RESIDING IN CARE HOMES 
Mutation frequency of pathogenic genes in familial Alzheimer’s disease in China  Jianping Jia, Liyong Wu, Wei Qin, Dan Li, Luxi Shen, Hanzhi Li, Qianqian.
Cerebrospinal fluid biomarkers for Alzheimer's disease are associated with neuropathology in cortical brain biopsy  Toni Seppälä, Ossi Nerg, Anne Koivisto,
Uwe Walter, David Školoudík, Daniela Berg 
Peroperative transcranial sonography for electrode placement into the targeted subthalamic nucleus of patients with Parkinson disease: technical note 
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Trajectory of multi-dimensional caregiving burden in chinese informal caregivers for dementia: Evidence from exploratory and confirmatory factor analysis.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Interaction network of tau protein, beta-amyloid protein, and amyloid protein precursor under oxidative stress in Alzheimer’s disease  Eduardo de Souza/S.
INCREASED CSF LEVELS OF BIOMARKERS FOR NEURODEGENERATION IN FTLD-GRN MUTATION CARRIERS  Joery Goossens, Sara Van Mossevelde, Tobi Van den Bossche, Anne.
SERUM NEUROFILAMENT LIGHT PROTEIN PREDICTS CLINICAL OUTCOME IN TRAUMATIC BRAIN INJURY  Pashtun Shahim, Magnus Gren, Victor Liman, Ulf Andreasson, Niklas.
The differential diagnosis of amnestic mild cognitive impairment and Alzheimer's disease dementia by hippocampal volume measurement with MR in a chinese.
Localization of Hippocampal atrophy in Alzheimer's disease
INVESTIGATION OF 99MTC-LABELED CLIOQUINOL DERIVATIVE ON AMYLOID PLAQUE SPECIFICITY BY USING AN ANIMAL MODEL OF ALZHEIMER'S DISEASE  Ayfer Yurt KIlçar,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Christine Bredfeldt, Kristen Rice, Lisa Alecxih 
SMARTPHONE TECHNOLOGY TO MEASURE HEALTH CHARACTERISTICS IN OFFSPRING OF PATIENTS WITH DEMENTIA: THE IVITALITY PROOF-OF- PRINCIPLE STUDY  Liselotte Wijsman,
From: What do we perceive in a glance of a real-world scene?
Martina Bocchetta, Elizabeth Gordon, Emily Manning, David M
KETOGENIC DIET EFFECTS ON BRAIN KETONE METABOLISM AND ALZHEIMER'S DISEASE CSF BIOMARKERS  Suzanne Craft, Bryan J. Neth, Akiva Mintz, Kiran Sai, Nora Shively,
The effect of using a conditional discrimination procedure to teach name-face relation to a person diagnosed with dementia  Hanna S. Steingrimsdottir,
Application of Resource Utilization in Dementia (RUD) instrument in a global setting  Anders Wimo, Anders Gustavsson, Linus Jönsson, Bengt Winblad, Ming-Ann.
LATENT-FACTOR STRUCTURE OF THE DELCODE STUDY NEUROPSYCHOLOGICAL TEST BATTERY  Steffen Wolfsgruber, Luca Kleineidam, Jannis Guski, Oliver Peters, Katharina.
Validation of a new language screening tool with stroke in chinese: The mandarin version of language screening test (MLAST)  Hongyan Yang, Shenghua Tian,
HYPERGLYCEMIA: PREDISPOSITION FOR MICROEMBOLI, STROKE, AND WHITE MATTER CHANGES  Leila Parand, Saif Bushnaq, Yue Wang, Lenora Mathes, Dinesh Jillella,
Marjolein Bulk, Linda van der Graaf, Walid M
Colin Groot, Chris W. J. van der Weijden, Wiesje M
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Japanese brain bank network for neuroscience research
BIOLOGICAL PATHWAYS FOUND IN COMMON BETWEEN ALZHEIMER’S DISEASE AND MAJOR DEPRESSION: A STUDY ON MICRORNA EXPRESSION IN A SYSTEMATIC REVIEW  Ana Paula.
Community environment and incident dementia: Results from the three-city study  Claudine Berr, Laure Anne Gutierrez, Sylvaine Artero, Catherine Helmer,
Effect of hypertension and antihypertensive medication on executive function, brain atrophy, and white matter hyperintensities  Shannon L. Risacher, Li.
Application of Resource Utilization in Dementia (RUD) instrument in a global setting  Anders Wimo, Anders Gustavsson, Linus Jönsson, Bengt Winblad, Ming-Ann.
Quiz Page August 2007 American Journal of Kidney Diseases
Deconstructing language disintegration: Primary progressive aphasias have specific tractographic signatures  Colin Mahoney, Ian Malone, Ged Ridgway, Aisling.
LIFESPAN OF ONE FOCUSED ULTRASOUND MEDIATED BLOOD-BRAIN BARRIER TREATMENT IN A MOUSE MODEL OF ALZHEIMER'S DISEASE  Charissa Poon, Kullervo Hynynen  Alzheimer's.
Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective  Matthew Baumgart, Heather M. Snyder,
Introduction: Evolution of military and veterans brain health research
Shruti Mishra, Brian Andrew Gordon, Karl A
Comparison of visual and quantitative florbetapir-PET reads in subjects with early Alzheimer's disease for assessing amyloid burden  Bradley Wyman, Yahong.
A biomarker signal: Context-dependent hippocampal fMRI connectivity analysis of clinical trial measures in Alzheimer's disease  Donald McLaren, Reisa.
Sulantha S. Mathotaarachchi, Tharick A
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
The incremental diagnostic value of 18F-florbetapir imaging in naturalistic patients with cognitive impairment: The India-FBP study  Marina Boccardi,
Added value of 11C-PiB-PET imaging in the diagnosis of Alzheimer's disease  Kristian Frederiksen, Anne-Mette Hejl, Ian Law, Steen Hasselbalch, Gunhild.
Mark D. Meadowcroft, Douglas G. Peters, Carson J
COGNITIVE COMPLAINTS IN OLDER ADULTS AT RISK FOR ALZHEIMER’S DISEASE ARE ASSOCIATED WITH ALTERED RESTING STATE NETWORKS  Joey A. Contreras, Joaquín Goñi,
Distinct [18F]AV1451 retention patterns in clinical variants of Alzheimer’s disease  Rik Ossenkoppele, Daniel Schonhaut, Suzanne Baker, Andreas Lazaris,
MR-less cortical surface-projection of PET images from 11C- and 18F-labeled radiotracers  Vincent Doré, Pierrick Bourgeat, Luping Zhou, Jurgen Fripp,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
GREY MATTER CONNECTIVITY IS ASSOCIATED WITH CLINICAL PROGRESSION IN NON-DEMENTED, AMYLOID POSITIVE PATIENTS  Betty M. Tijms, Mara ten Kate, Sander C.J.
Alzheimer's Association towards Guidelines for Dementia Care Practice: Recommendations with emphasis on high-quality, person-centered care in long-term.
Brain amyloid deposition and metabolism in early and late mild cognitive impairment  Jared Rowley, Liyong Wu, Sara Mohades, Marina Dauar, Antoine Leuzy,
Tharick A. Pascoal, Sulantha S
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
INTRINSIC CONNECTIVITY NETWORKS IN POSTERIOR CORTICAL ATROPHY: A ROLE FOR THE PULVINAR?  Carolyn A. Fredericks, Jesse Brown, Jersey Deng, Rik Ossenkoppele,
Automated detection of beta-amyloid–related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI 
Extracting white matter hyperintensities in Alzheimer's disease risk and aging studies using supervised segmentation methods  Vamsi Ithapu, Vikas Singh,
BRAIN AMYLOIDOSIS AND COGNITIVE DECLINE IN MCI: 12-MONTH FOLLOW-UP
Michael Navitsky, Abhinay D. Joshi, Michael D. Devous, Michael J
ONE-YEAR GLOBAL OUTCOME OF A COMPREHENSIVE, INDIVIDUALIZED, PERSON CENTERED MANAGEMENT (CI-PCM) PROGRAM + MEMANTINE IN ADVANCED AD: A RANDOMIZED CONTROLLED.
Bistra Iordanova, Matthew C. Murphy, William E. Klunk, Alberto L
FIGURE 1. Axial views of the midbrain of one Parkinson's disease patient as observed with a standard clinical 3T MRI ... FIGURE 1. Axial views of the midbrain.
Presentation transcript:

MRI PATCH-BASED IMAGING BIOMARKER FOR AUTOMATIC DETECTION OF PARKINSON’S DISEASE  Vladimir S. Fonov, Mahsa Dadar, Xiao Yiming, D. Louis Collins  Alzheimer's & Dementia: The Journal of the Alzheimer's Association  Volume 12, Issue 7, Pages P1088-P1089 (July 2016) DOI: 10.1016/j.jalz.2016.06.2272 Copyright © 2016 Terms and Conditions

Figure 1 Midbrain area of the population-specific anatomical average of T1w scans from PPMI dataset with colour labels showing substantia nigra (navy and turquoise) and subthalamic nucleus (green and yellow) used to calculate grading scores. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2016 12, P1088-P1089DOI: (10.1016/j.jalz.2016.06.2272) Copyright © 2016 Terms and Conditions

Figure 2 Grading distribution across STN and SN. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2016 12, P1088-P1089DOI: (10.1016/j.jalz.2016.06.2272) Copyright © 2016 Terms and Conditions

Figure 3 Receiver operating characteristic (ROC) curve for classification between PD and NC based on grading of each structure. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2016 12, P1088-P1089DOI: (10.1016/j.jalz.2016.06.2272) Copyright © 2016 Terms and Conditions