Viral Diseases 15.5-24 Microbiology.

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Viral Diseases 15.5-24 Microbiology

15.5 Viral Diseases of the Nervous System Rabies-encephalitis 55,000 deaths/year Symptoms: hydrophobia, paranoia, terror, mania, hallucinations & delirium. Early detection is key, once symptoms have presented survival is rare.

15.5 Viral Diseases of the Nervous System Poliomyelitis Muscle weakness & paralysis World-wide epidemic 1880-1910 1950s Jonas Salk vaccine

15.5 Viral Diseases of the Nervous System Hantavirus- hemorrhagic fever with renal syndrome Rodent excrement Hantavirus Pulmonary Syndrome (HPS) 60% fatality rate

15.5 Viral Diseases of the Nervous System Arthropod vectors-mostly ticks & mosquitos Arboviral encephalitis West Nile Virus Zika

15.6 Prion Diseases of the Nervous System Bovine Spongiform Encephalopathy (BSE)-”mad cow” disease Varian Creutzfeldt-Jakob Disease (vCJD) in humans 1986-1998 outbreak in UK 229 deaths No treatment 100% fatal

15.9 Viral Diseases of the Cardiovascular & Lymphatic Systems Burkitt's Lymphoma Cancer African children

15.9 Viral Diseases of the Cardiovascular & Lymphatic Systems Epstein-Barr virus (EBV) Mononucleosis “kissing” disease Lupus Rheumatoid Arthritis Multiple Sclerosis (MS)

15.9 Viral Diseases of the Cardiovascular & Lymphatic Systems Cytomegalovirus (CMV) Herpes family 50-80% of US adults Chikungunya (CHIKV) Mosquito borne Severe Fever & Joint pain Viral Hemorrhagic Fever (VHF) Ebola

15.13 Viral Diseases of the Respiratory System Common Cold-200 types Rhinovirus most common Viral pneumonia-RSV, hPIV, SARS Mostly children affected Coryza & Influenza Air-borne Birds and Mammals 1918-1920 Spanish Flu Pandemic 50-100 million deaths

15.18 Viral Diseases of the Digestive System Mumps-infection in salivary glands, pancreas & testicles MMR vaccination Hepatitis-liver cirrhosis, alcoholics Viral Gastroenteritis Rotavirus-children Norovirus-adults

15.24 Viral Diseases of the Reproductive System Genital Herpes U.S. 45 million infected No cure Human Papilloma Virus (HPV) Genital Warts Cervical Cancer Gardasil Tree Man

15.24 Viral Diseases of the Reproductive System Human Immunodeficiency Virus (HIV) Acquired Immunodeficiency Syndrome (AIDS) Retrovirus-no cure or vaccine 2015 36.7 million infected worldwide