Prevalence, characteristics, and predictors of early termination of cardiovascular clinical trials due to low recruitment: Insights from the ClinicalTrials.gov.

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Presentation transcript:

Prevalence, characteristics, and predictors of early termination of cardiovascular clinical trials due to low recruitment: Insights from the ClinicalTrials.gov registry Sabrina Bernardez-Pereira, MD, MS, Renato D. Lopes, MD, PhD, Maria Julia Machline Carrion, MD, MS, Eliana Vieira Santucci, MS, Rafael Marques Soares, MS, Matheus de Oliveira Abreu, MS, Ligia Nasi Laranjeira, MS, Dimas T. Ikeoka, MD, PhD, Ana Denise Zazula, MD, Frederico Rafael Moreira, MS, Alexandre Biasi Cavalcanti, MD, PhD, Evandro Tinoco Mesquita, MD, PhD, Eric D. Peterson, MD, MPH, Robert M. Califf, MD, Otavio Berwanger, MD, PhD American Heart Journal Volume 168, Issue 2, Pages 213-219.e1 (August 2014) DOI: 10.1016/j.ahj.2014.04.013 Copyright © 2014 Mosby, Inc. Terms and Conditions

Figure 1 Study design—flowchart of systematic analysis of cardiovascular interventional trials registered in ClinicalTrials.gov. American Heart Journal 2014 168, 213-219.e1DOI: (10.1016/j.ahj.2014.04.013) Copyright © 2014 Mosby, Inc. Terms and Conditions

Figure 2 Multivariable logistic regression analysis assessing predictors of early termination of cardiovascular clinical trials due to low recruitment. American Heart Journal 2014 168, 213-219.e1DOI: (10.1016/j.ahj.2014.04.013) Copyright © 2014 Mosby, Inc. Terms and Conditions