Frequency of Helicobacter Pylori Infection among Type II Diabetic and Non-Diabetics Patients with Functional Dyspepsia Hanan Mahmoud Fayed1 , Mohamed A. Alsenbesy2, Mohamed Sabry El-rawy2, Ahmed Baghdady3 1-Clinical and Chemical pathology Department - Qena Faculty of medicine, South Valley University. 2-,Internal Medicine Department - Qena Faculty of medicine, South Valley University. 3- Internal Medicine Department - Sohag Faculty of medicine-Sohag University. by Dr. Mohamed Alsenbesy Lecturer of Internal Medicine Gastroenterology & Endoscopy Qena Faculty of Medicine South Valley University , Egypt
Definitions Helicopacter pylori is a microorganism (Bacterium) affecting the stomach and was found to be related to ulcer formation
Peptic Ulcer means a defect in the mucous membrane lining the stomach or the Duodenum
Type 2 diabetes is disease of the older population with incresed glucose level in the blood (Sugar disease)
Functional Dyspepsia means upper abdominal symptoms without ulcer
Diabetes is a disease associated with decreased immunity Patients are susseptible to many bacterial and viral infections
Is diabetes a risk for Helicobacter pylori and stomach diseases? The aim of this study: to determine the frequency of H pylori infection among patients with symptoms of dyspepsia in type 2 diabetics compared to other normal population.
Patients and Method: A cross sectional case-control study was carried out 45 with T2DM (group 1); 45 non-diabetic patients as controls (group 2); to study the role of H. pylori in pathogenesis of non-ulcer dyspepsia in diabetic patients. The sero-prevalence of H. pylori IgG antibodies was evaluated using commercial enzyme linked immunosorbent assay (ELISA).
Results in (group 1) T2DM and dyspepsia; they were 11 (24.4%) males and 34(75.6%) females with a mean age of 57.31 ± 8.864 years compared to (group 2) non-DM subjects and dyspepsia; they were14 (31.1%) males and 31(68.9%) females with a mean age of 53.64 ± 11.14 years
Results The serology test for H. pylori was positive in 40% T2DM and 31.1% non-diabetic patients (non-significant). There was no statistical significant relation in both groups regarding the rate of H Pylori infection.
Conclusion there is no significant increase in prevalence of H pylori infection among T2DM patients. H pylori infection is not related to age of the patients, their sex, BMI, duration of diabetes nor to glycemic status.
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