History of Neurology Early New York Neurology – Part 2 The New York Neurologic Institute, Houston Merritt & Lewis Rowland Richard J. Barohn, MD Gertrude and Dewey Ziegler Professor of Neurology The University of Kansas Medical Center

The Neurological Institution of New York Columbia University, College of Physicians and Surgeons Founded 1909 Chairmen of Neurology: Joseph Collins 1909-1919 Frederick Tilney 1920-1935 Walter W. Palmer 1935-1939 Tracy J. Putnam 1939-1946 Edwin Zabriskie 1946-1948 H. Houston Merritt 1948-1967 G. Milton Shy 1967-1967 Richard L. Masland 1967-1973 Lewis P. Rowland 1973-1998 Timothy A. Pedley 1998-2011 Richard Mayeux 2011-present New York celebrated its 100th Anniversary in 2009 https://vimeo.com/12945281 The first Neurological Institute of New York at 149 East 67th Street. View looking north across 67th Street

H. Houston Merritt, MD 1902-1979 Born in Washington, North Carolina UNC/Vanderbilt/MD at John Hopkins - 1926 Boston City Hospital, Neurology - 1928 Neuropathy in Germany - 1930 Harvard Faculty 13 years Professor & chair of Neurology at Columbia Univ. & Director Neuropsychiatry Montefiore Hospital - 1944 Professor & Director, Dept. Neurology at Columbia - 1948-1967 Dean, College of Physicians & Surgeons - 1958-1970 Henry and Lucy Moses Professor of Neurology - 1963 Neurological Institute became a major center for neurological training and research under Dr. Merritt Taught many future leaders in Neurology including Dewey Ziegler, Robert Fishman, and Lewis Rowland

H. Houston Merritt, MD 1902-1979 Discovered phenytoin (Dilantin) anticonvulsant properties - 1938 With Tracy Putnam at BCH Primarily phenobarbital Experimental methods were basis to other anti- seizure drugs CSF, neurosyphilis, headache, stroke, MS, genetic disease 1938 1938

H. Houston Merritt, MD Other Contributions/Books 215 papers, 15 books A Textbook of Neurology - 1955 5 editions, sole author Still in print-12 edition- Rowland and Pedley The Cerebrospinal Fluid (1937) with Fremont Smith Neurosyphilis (1946) with RD Adams & HC Solomon

Merritt’s Textbook of Neurology Ed by Lewis P Merritt’s Textbook of Neurology Ed by Lewis P. Rowland “My” 2nd line neurology textbook as a resident 1st ed. 1955 8th ed. 1989 2nd ed. 1959 9th ed. 1994 3rd ed. 1963 10th ed. 2000 4th ed. 1967 11th ed. 2005 5th ed. 1973 12th ed. 2009 6th ed. 1979 13th ed. 2015 7th ed. 1984 2nd ed. 1959 7th ed. 1984 9th ed. 1994 10th ed. 2000 11th ed. 2005 12th ed. 2009 13th ed. 2015

H. Houston Merritt, MD 1902-1979 Died from stroke and NPH Even though in his career he was skeptical about NPH His students in NY were treating him - disagreed over course of action Transferred to MGH Succumbed to after-effects of a neurosurgical operation at the age of 79

Who is This? Dewey Ziegler, MD H. Houston Merritt, MD

Neuro Family Tree: Descendants of Merritt H. Houston Merritt R. Fishman (UCSF) D. Ziegler (KU) L. Rowland (Columbia, NY)

Lewis P. Rowland, MD 1926-2017 YEAR ACHIEVEMENT 1942 – 1948 B.S. & M.D. from Yale University Graduated cum laude & elected to Alpha Omega Alpha 1948 – 1950 Research Assistant; Columbia University Intern in Medicine; Yale University 1950 – 1953 Residency training under H. Houston Merritt, MD Dewey Ziegler was his Chief Resident; Robert Fishman was also a resident Columbia University, New York 1953 – 1954 Fellowship at NIH; Shy was Chief NINDB Fired due to relationship w/ American Association of Interns & Med Students 1954 – 1957 Assistant Neurologist, Adjunct Attending Neurologist Montefiore Hospital, New York Instructor then Associate in Neurology 1957 – 1961 Fellow in Biochemistry College of Physicians & Surgeons, Columbia University 1957 – 1967 Assistant, Associate, then Professor of Neurology Columbia University Assistant, Associate, then Professor, of Neurology Columbia-Presbyterian Medical Center 1967 – 1973 Professor & Chairman, Department of Neurology University of Pennsylvania School of Medicine Lewis P. Rowland, MD 1926-2017

Lewis P. Rowland, MD 1946-2017 YEAR ACHIEVEMENT 1973 – 1998 Chairman of Neurology & Director of the Neurology Service Presbyterian Hospital, New York & Columbia University College of Physicians & Surgeons Director The Neurological Institution of New York 1974 – 1998 Henry and Lucy Moses Professor of Neurology Columbia University Medical Center, New York Co-Director of the H. Houston Merritt Clinical Research Center for Muscular Dystrophy & Related Diseases 1989 – 1999 Founder & Co-Director of the Eleanor and Lou Gehrig MDA/ALS Center 1977 – 1987 Editor-in Chief of Neurology 1979 – 2015 Editor, Merritt’s Neurology Textbook (8 editions; 6th – 13th) 1980 – 1981 President, American Neurological Association 1989 – 1991 President, American Academy of Neurology; Chairman of the Academy’s Education and Research Foundation 2000 – 2009 Chief Editor, Neurology Today Lewis P. Rowland, MD 1946-2017

Fishman, Rowland & Wives Ziegler Celebration - 2002 Fishman, Rowland & Wives

Ziegler Celebration - 2002 Lewis “Bud” Rowland, Dewey Ziegler & Robert Fishman

10 Years of Ziegler Professorship Lectures 2007 – Lewis P. Rowland, MD 2008 – Louis R. Caplan, MD 2009 – Jerry R. Mendell, MD 2010 – Martin A. Samuels, MD 2011 – Harold P. Adams, MD 2012 – John C. Morris, MD 2013 – Eelco F. Wijdicks, MD, PhD 2014 – Thomas G. Brott, MD 2015 – Stephen Hauser, MD 2016 – James C. Grotta, MD 2017 – Frank Gilliam, MD

First Year of Ziegler Professorship – June 2007 Barbara Atkinson, Lewis “Bud” Rowland, Rick Barohn, Dewey Ziegler, Gary Gronseth & Dale Seuferling

Bud & Esther Rowland