Creating more electron carriers Kreb’s Cycle Creating more electron carriers

Overivew TODAY’S GOALS: Review big steps of aerobic cellular respiration Take a look at mitochondrion structure Kreb’s cycle key ideas

Cellular Respiration

Cellular Respiration Phases of aerobic cellular respiration Glycolysis (the beginning of all cellular respiration) Transition / Link / Acetyl-CoA reaction Krebs cycle Electron transport system These phases are nothing more than metabolic reactions involving the conversion of glucose & other molecules into carbon dioxide & water The resulting energy released from this conversion is used to produce ATP

Cellular Respiration Act it out!

Cellular Respiration

Cellular Respiration Mitochondria structure Similar in arrangement to the chloroplast It is a double membrane organelle The intermembrane space is bounded by the outer membrane & the inner membrane The inner membrane encloses a central space called the matrix. The transition reaction & Krebs cycle occur within matrix. The inner membrane is folded into cristae. The electron transport system is located in the inner membrane or cristae.

Cellular Respiration

TEM of a Mitochondrion a. c. b. http://t2.gstatic.com/images?q=tbn:ANd9GcS_NZIhVg9POlqcGKOUUEjPu0oYxmRLXhmPnp-M2nAs6DGA_Y2-

Cellular Respiration Transition, Link, or Acetyl-CoA reaction Occurs in the matrix of the mitochondrion Purpose: Creation of acetyl CoA for Kreb’s cycle; creation of reduced electron carriers (NADH) Reactants = 2 pyruvates, 2 co-enzyme A (CoA), 2 NAD+ Products = 2 acetyl CoA, 2 NADH + H+, 2 CO2

Cellular Respiration

Cellular Respiration Krebs Cycle Occurs in the matrix of the mitochoncrion Reactants = 2 acetyl CoA (from? __________), 2 ADP, 2 Pi, 6 NAD+, 2 FAD Products = 2 ATP, 6 NADH, 2 FADH2, 4 CO2 FAD – flavin adenine dinucleotide – an electron carrier similar to NAD+ During Krebs cycle both NAD+ & FAD are reduced to NADH & FADH2 respectively If both of these molecules are being reduced, what has to be happening to other molecules?

Kreb’s Cycle Acetyl-CoA feeds the two carbons it got from pyruvate (during the link reaction) into the cycle. NADH, FADH2, a little ATP, and CO2 are generated.

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