HIP Buffet: Mapping Your Career with NIH 2/18/2018 Purpose of NIH Career Development Programs: To provide protected time for individuals to further develop their research expertise.

General Tips about Mentored K Awards Understand the intent of the mentored K award. To help promising new investigators achieve research independence (i.e., to compete successfully for R01 funding). Preparing for the R01 grant application you will submit at the end of the K award should be the organizing principle of the K grant application.

Develop a career development training plan that is uniquely suited to you. Given your previous training and research experience, and your short- and long-term career goals, propose a mix of didactic training and “hands- on” research experience that make perfect sense for you (and only you). Degree-granting programs are appropriate for candidates with little or no previous formal training in research, but even these programs should be “customized” whenever possible.

K Awards Individual Awards (Mentored): Mentored Independent Depending on the award, for early, mid-, or senior career levels Depending on the award, all doctorates or restricted to clinical doctorates Institutional Awards (Mentored): Institution applies and receives the award Institution selects trainees 5 K12 awards at OHSU

In addition to NIH K awards, consider… NSF Faculty Early Career Development VA CDA awards Career development awards from scientific organizations such as American Cancer Society, American Heart Association Professional organizations. Consider your research focus, career

NSF Faculty Early Career Award Provide stable support for 5 years (≥400K in most Directorates) for career development of outstanding new teacher-scholars Must be tenure track ore equivalent as an Asst Prof Can apply twice Related to integration of research and education, either students, under-represented, community Otherwise, proposal structure and review very similar to NIH K awards

Mentored K Awards K01: Mentored Research Scientist Development Award K07: Cancer Prevention, Control, Behavioral Sciences, and Population Sciences Career Development Award K08: Mentored Clinical Scientist Development Award for Laboratory Research K22: Research Career Award for Transition to Independence K23: Mentored Patient-Oriented Research Development Award K25: Mentored Quantitative Research Development Award K99/R00: NIH Pathway to Independence Award K12: Institutional Mentored Research Scientist Development Program (Clinical)

K01- Mentored Research Scientist Development Award HIP Buffet: Mapping Your Career with NIH 2/18/2018 K01- Mentored Research Scientist Development Award Support for intensive, supervised career development in biomedical, behavioral, or clinical sciences leading to research independence. 5 year, 75% FT effort Define the need for 3-5 years of additional supervised research, can be in new area for applicant or one that substantially adds to research capability of applicant Ideal candidate varies by institute Career hiatus, under-represented in research, disabled, disadvantaged background, interruption of research career

NIH Pathway to Independence (PI) Award K99 / R00 HIP Buffet: Mapping Your Career with NIH 2/18/2018 NIH Pathway to Independence (PI) Award K99 / R00 Phase 1, 1-2 years of mentored support Phase 2, 3-4 years of independent support Phase 2 contingent on securing independent research position, evaluation of research plan, positive career development Initial application must have proposal for research project as independent investigator in Phase 2

Success Rate of K01 Awards

Success Rate of K23 Awards

Success Rate of K99 Awards

K Awards – Common Themes HIP Buffet: Mapping Your Career with NIH 2/18/2018 K Awards – Common Themes Most demand 75% FT commitment x 3-5 yrs Buys protected time, formal research training and mentored research experience Pay $75K, $90K, or 75% of true salary up to cap Usually $25K for research support but up to $50K For most, prior R03, R21 OK; others are not OK Cannot pay the other 25% from federal money MOST IMPORTANTLY, each institute may apply each PA differently Deadlines in Feb, June, Oct

Common Features: Eligibility Doctoral degree (generally) US Citizen, Non-Citizen National, Permanent Resident (except K99/R00); Citizenship requirement met at time of award, not application Previous NIH PD/PI may be Ineligible Usually PD/PI on R03 or R21 is OK (except K99/R00) PD/PI on R01 or subproject PD/PI on a P01 is NOT OK For K99/R00: Eligibility changed to target investigators who have no more than 4 years of postdoctoral research experience (previously 5 years) Read the Eligibility Section of the Funding Opportunity Announcements (FOAs) carefully!

Common Features: Costs Some costs vary widely across NIH ICs. Review specific Program Announcements carefully. Salary/fringe benefits: Most pay $100K per year for 0.75 FTE Fringe benefits Salary supplementation OK, but must be with non-Federal funds and not require extra duties that would interfere with K activities Research/development costs: Generally $25,000 to $50,000 Commonly used for: supplies, equipment, technical personnel, travel to research meetings or training, tuition/fees, computational services

Mentored K Awards: Review Overall Impact Score Scored Review Criteria Candidate Career Development Plan Research Plan Mentor(s), Consultant(s), and Collaborator(s) Environment and Institutional Commitment to the Candidate