PHARMA CEUTICAL MANAGEMENT

The top 10 pharma companies India COMPANY RANK VALUE IN CRS TOTAL UNITS % MS. GROWTH % ABBOTT* 1 3,520.86 957,310,325 6.95 15.35 CIPLA 2 2,596.32 881,850,007 5.13 10.85 RANBAXY* 3 2,415.21 642,600,371 4.77 14.24 GLAXOSMITHKLINE* 4 2,070.15 1,061,666,309 4.09 9.06 SUN 5 1,914.86 408,583,758 3.78 16.68 ZYDUS CADILA 6 1,879.55 796,388,741 3.71 12.72 ALKEM 7 1,684.93 459,369,887 3.33 16.59 MANKIND 8 1,673.50 535,537,402 3.31 25.22 PFIZER 9 1,554.86 579,738,343 3.07 11.79 LUPIN LIMITED 10 1,359.89 340,178,544 2.69 11.92 Gsk and pfizer are the two mncs in the list of top 10 pharma companies in India

COMPANY RANK VALUE IN CRS TOTAL UNITS % MS. GROWTH % MACLEODS PHARMA 11 1,182.24 307,515,396 2.34 44.63 INTAS PHARMA* 12 1,180.72 301,864,909 2.33 28.54 ARISTO PHARMA* 13 1,163.16 413,550,750 2.30 8.92 SANOFI AVENTIS* 14 1,089.74 469,259,728 2.15 13.66 EMCURE* 15 1,050.80 182,197,132 2.08 18.75 DR REDDYS LABS 16 1,048.11 254,967,068 2.07 6.77 WOCKHARDT-MERIND* 17 1,035.71 486,417,335 2.05 19.87 TORRENT PHARMA 18 1,014.76 291,087,779 2.00 15.43 U S V 19 898.55 362,025,129 1.77 21.64 ALEMBIC 20 896.58 249,663,324 9.04 MICRO LABS* 21 881.88 258,839,502 1.74 10.64 NOVARTIS INTL.* 22 869.57 242,681,650 1.72 13.59 GLENMARK PHARMA 23 789.80 145,008,658 1.56 20.13 FDC 24 785.22 364,100,164 1.55 5.53 UNICHEM* 25 728.64 240,716,000 1.44 8.33

Top Brands THERAPEUTIC CLASS/BRANDS RANK VALUE IN CRS % MS. GROWTH % COREX Pfizer 1 210.63 0.42 1.50 HUMAN MIXTARD30/70 Abbot 2 209.56 0.41 30.42 VOVERAN Novartis 3 190.05 0.38 4.17 AUGMENTIN GSK 4 184.48 0.36 14.43 REVITAL Ranbaxy 5 177.02 0.35 14.15 PHENSEDYL COUGH Abbot health 6 174.56 0.34 -14.03 MONOCEF Aristo 7 164.65 0.33 18.26 DEXORANGE Franco indian 8 152.80 0.30 5.12 TAXIM Alkem 9 151.29 10.70 MOX Ranbaxy 10 145.17 0.29 13.06 Atp- aristo pharma

Components of pharmaceutical business : Pharmaceutical business is a convergence of distinct business specialities Components of pharmaceutical business : Big Pharma(Innovator companies) API manufacturers Biotechnology companies Speciality pharmaceutical manufacturers CROs Generic manufacturers Chemistry based generics Biogenerics/Biosimilars Excipient manufacturers Medical devices companies

Big Pharma(Innovator companies) The big pharmaceutical manufacturers are companies focused on pure, research-based pharmaceutical and combination products. Speciality Pharma companies  Specialty pharmaceutical manufacturers identify opportunities to develop niche products and used those endeavours to grow and mature. Generics Generics manufacturers benefit from a growing volume of overall prescriptions and the popularity of cheaper generics when patents expire Strong growth and consolidation have resulted in large, well- financed organizations Diclofenac voveran activa (generic) (branded) (branded generic)

CROs A person or an organization (commercial, academic, or other) contracted by the sponsor to perform one or more of a sponsor's trial-related duties and functions. API Business : Companies exclusively engaged in the manufacture of active constituents of the formulation Biotech firms: Biotechnology is a field of applied biology that involves the use of living organisms and bioprocesses in  engineering, technology, medicine and other fields requiring bio products

Indian Pharmaceutical industry 3rd largest in the world by volume 13th largest in the world by value Indian pharma industry has witnessed rapid growth Domestic Market : 62,055 cr. Export market : 42,154 cr 25000+ pharmaceutical companies in India Reference: mckinsey report

Business ( enterprise) A business (also known as enterprise or firm) is an organization engaged in the trade of goods, services, or both to consumers In Pharma Business Customer Consumer

Types of business and enterprise Corporation: A corporation is created under the laws of a state as a separate legal entity that has privileges and liabilities that are distinct from those of its members Cooperative:  a cooperative is a limited liability business that can organize for-profit or not-for-profit Partnership : A partnership is an arrangement where parties agree to cooperate to advance their mutual interests Sole proprietorship : it is owned and run by one individual and in which there is no legal distinction between the owner and the business Limited liability company:  It is a legal form of company that provides limited liability to its owners

Healthcare in India Provided both by private and public players treatment facilities provided by the Government Through primary, secondary or tertiary levels of state healthcare institutions (primary health centers PHC) health care workers in the country is a little over 8 per 10,000 population Allopathic physicians - 31% nurses and Midwives -30% Pharmacists-11% practitioners of traditional systems of medicine-9% The Central Government's share of cost of medicines in its total health budget Is around 12% Medicines account for up to 50-60%of healthcare costs in India Therefore 354 drugs proposed in the National List of Essential Medicines (NLEM) under price cap.

Healthcare service providers Public: Government healthcare National Rural Health Mission (NRHM) CGHS- central government health scheme Private healthcare providers Major healthcare provided by private players Apollo hospitals Fortis hospitals Max hospitals

Pharmacist positioning in healthcare over a million pharmacists in India 55% community pharmacist 20% in hospital 10% in industry and regulatory 2% in academia Every year nearly 20000 D.Pharm., 30,000 B.Pharm., 6000 M.Pharm., and 700 Pharm.D. students graduate in the country

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