University of Minnesota Veterinary Diagnostic Laboratory Activities & Interactions Dr. Jerry Torrison Worthington, MN April 7, 2017

What do we do? Solve problems Disease surveillance Teach / Train Clinical diagnostic testing Research Disease surveillance Look for new or changing diseases Teach / Train DVM Scientists & pathology residents

Teach / Train / Partner

MVDL Clients and Networks Private Clients Local - Police - Animal Control State - Board of Animal Health - Department of Agriculture - Department of Health - Department of Natural Resources - Pollution Control Agency Other laboratories - University - Private Federal Networks USDA:APHIS DHS Veterinary Services ICLN: NAHLN HSIN NAHRS IIAD FISIS CDC FERN LRN FDA EPA AFN: Animal Feed Network Environmental Lab Response Network eLEXNET Vet-LIRN FBI

Surveillance Testing in 2016 Program AND Foreign Animal Diseases   Foot and Mouth Disease 298 Classical Swine Fever – USDA Surveillance 725 Pseudorabies – USDA Surveillance 3318 Avian Influenza 70,515 Exotic Newcastle Disease 9532 Vesicular Stomatitis Virus 1548 Swine Influenza Virus - USDA Surveillance 3372 (FY2016) Rabies 2248 Scrapie 161 Chronic Wasting Disease 1012 Koi Herpes Virus 8 Viral Hemorrhagic Septicemia 564

Surveillance Testing in 2016 Other Diseases Reportable to the Minnesota BAH   Brucellosis (B canis and sp.) 13,744 Equine Infectious Anemia 4099 Johne’s Disease 12,201 Q fever 413 Tularemia 32 positive Equine Herpes Myeloencephalopathy 2 Avian Encephalomyelitis 10 Avian Metapneumovirus 17,621 Mycoplasma gallisepticum 41,666 Mycoplasma Meleagridis 62,568 Mycoplasma Synoviae 72,672 Pullorum Typhoid 592 Salmonellla Enteritidis 107 positive

Surveillance Testing in 2016 Other Zoonotic and Emerging Diseases   Senecavirus A 4147 Ovine Progressive Pneumonia 4707 Toxoplasmosis 52 Canine Influenza 16 Borrelia burgdorferi 205

Problem Solving

Minnesota VDL Pathogen Discovery Virology Serology Molecular Development Pathogen Discovery Bacteriology Molecular Diagnostics Electron Microscopy Pathology & Histology

“Thus, what is of supreme importance in war is to attack the enemy's strategy.”

Evasion: Camouflage RNA viruses: PRRS Influenza Rotavirus ??

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Vascularization and Mineralization of Epiphyseal Cartilage in the Femur Carlson, 2010

How do we do it? High case volume High quality faculty & staff Close ties to veterinarians and industry

Laboratory Sections VDL Virology Serology Parasitology Bacteriology Molecular Diagnostics Immunohistochemistry Histology Pathology Repository Lab for Udder Health QA/QC Poultry Testing Lab Necropsy Molecular Development Electron microscopy Administration Accounting

Paul Gauguin 1888