Effects of β-erythropoietin treatment on left ventricular remodeling, systolic function, and B-type natriuretic peptide levels in patients with the cardiorenal.

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Presentation transcript:

Effects of β-erythropoietin treatment on left ventricular remodeling, systolic function, and B-type natriuretic peptide levels in patients with the cardiorenal anemia syndrome Alberto Palazzuoli, MD, PhD, Donald S. Silverberg, MD, Francesca Iovine, MD, Anna Calabrò, PhD, Maria S. Campagna, PhD, Maddalena Gallotta, MD, Ranuccio Nuti, MD American Heart Journal Volume 154, Issue 4, Pages 645.e9-645.e15 (October 2007) DOI: 10.1016/j.ahj.2007.07.022 Copyright © 2007 Mosby, Inc. Terms and Conditions

Figure 1 Mean LVEF values at start, 4 months, and 12 months of follow-up period in group A (EPO) and group B (placebo). Erythropoietin therapy improved LVEF after 12 months. American Heart Journal 2007 154, 645.e9-645.e15DOI: (10.1016/j.ahj.2007.07.022) Copyright © 2007 Mosby, Inc. Terms and Conditions

Figure 2 Mean LVSV at start, 4 months, and 12 months of follow-up period in group A (EPO) and group B (placebo). Erythropoietin therapy reduced LVSV after 4 and 12 months. American Heart Journal 2007 154, 645.e9-645.e15DOI: (10.1016/j.ahj.2007.07.022) Copyright © 2007 Mosby, Inc. Terms and Conditions

Figure 3 Relationship between BNP and Hb levels after 12 months in 2 groups: in EPO-treated patients, BNP decreased together with Hb increase. American Heart Journal 2007 154, 645.e9-645.e15DOI: (10.1016/j.ahj.2007.07.022) Copyright © 2007 Mosby, Inc. Terms and Conditions