Volume 62, Issue 5, Pages (November 2002)

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Volume 62, Issue 5, Pages 1732-1742 (November 2002) Determinants of outcome in ANCA-associated glomerulonephritis: A prospective clinico- histopathological analysis of 96 patients Herbert A. Hauer, Ingeborg M. Bajema, Hans C. Van Houwelingen, Franco Ferrario, Laure-Hélène Noël, Rüdiger Waldherr, David R.W. Jayne, Niels Rasmussen, Jan A. Bruijn, E. Christiaan Hagen Kidney International Volume 62, Issue 5, Pages 1732-1742 (November 2002) DOI: 10.1046/j.1523-1755.2002.00605.x Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 1 Scatter plots with regression line for the percentage of cellular crescents versus baseline glomerular filtration rate (GFR0;A), GFR at 18 months (GFR18;B), and corrected GFR at 18 months (CORGFR18;C). In panel A, r = -0.275, P = 0.007; in B, r = 0.029, P = 0.796; in C, r = 0.301, P = 0.006. Kidney International 2002 62, 1732-1742DOI: (10.1046/j.1523-1755.2002.00605.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 2 Scatter plots with regression line for the percentage of glomeruli with fibrinoid necrosis versus GFR0 (A), GFR18 (B), and CORGFR18 (C). In panel A, r = -0.111, P = 0.281; in B, r =0.309, P = 0.005; in C, r = 0.464, P < 0.001. Kidney International 2002 62, 1732-1742DOI: (10.1046/j.1523-1755.2002.00605.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 3 Scatter plots with regression line for the percentage of sclerotic glomeruli versus GFR0 (A), GFR18 (B), and CORGFR18 (C). In panel A, r = -0.297, P = 0.003; in B, r = -0.422, P < 0.001; in C, r = -0.307, P = 0.005. Kidney International 2002 62, 1732-1742DOI: (10.1046/j.1523-1755.2002.00605.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 4 Box plots for the severity of interstitial fibrosis versus GFR0 (A), GFR18 (B), and CORGFR18 (C). In panel A, r = -0.482, P < 0.001; in B, r = -0.449, P < 0.001; in C, r = -0.059, P = 0.601. Kidney International 2002 62, 1732-1742DOI: (10.1046/j.1523-1755.2002.00605.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 5 Scatter plot with regression line for GFR0 versus GFR18 (r = 0.673,P < 0.001). Kidney International 2002 62, 1732-1742DOI: (10.1046/j.1523-1755.2002.00605.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 6 Scatter plot of the estimated GFR18 versus the measured GFR18 (r2 = 0.602, SD = 19.07 mL/min). The estimated GFR18 was calculated by the following formula: Estimated GFR18 (mL/min) = 17 + 0.71 × GFR0 (mL/min) + 0.34 × fibrinoid necrosis (%) + 0.33 × segmental crescents (%). Kidney International 2002 62, 1732-1742DOI: (10.1046/j.1523-1755.2002.00605.x) Copyright © 2002 International Society of Nephrology Terms and Conditions