Warm-Up (1/27) Answer the following questions, and explain in a complete sentence why each answer is correct. Name Date Period If a paramecium (a one-celled.

Slides:



Advertisements
Similar presentations
Any change in the DNA base sequence is called a mutation
Advertisements

Transcription & Translation Worksheet
GENE MUTATIONS aka point mutations. DNA sequence ↓ mRNA sequence ↓ Polypeptide Gene mutations which affect only one gene Transcription Translation © 2010.
Nature and Action of the Gene
Mutations Mutation- a change in the DNA nucleotide sequence
Sex cell (gametes = egg and sperm)
To demonstrate understanding, after this lesson, you should be able to  define mutations  explain how mutations occur when – DNA Replication or Meiosis.
List diseases that can be caused by mutations Cystic fibrosis Sickle cell anaemia Tay-Sachs disease Phenylketonuria Colour-blindness Cancers
Chapter 14 The Human Genome.
PART 1 - DNA REPLICATION PART 2 - TRANSCRIPTION AND TRANSLATION.
Transcription and Translation. If DNA never leaves the nucleus, how can the DNA message get to the site of protein production, the ribosome?
Protein Synthesis-- Transcription and Translation.
Topic 4.1 Chromosomes, Genes, Alleles and Mutations.
TTGACATACCCGTAAT What would the complementary strand of this DNA molecule read? AACTGTATGGGCATTA.
Chapter 14 Homework is due on Sunday, January 25 at 11:59 pm The Chapter 13 and 14 test is on Monday.
Gene Mutations. O A mutation is a permanent change in the DNA sequence of a gene. O Any change in this sequence is likely to change the message transcribed.
Mutations are changes in DNA that may or may not affect phenotype. Some mutations affect a single gene, while others affect an entire chromosome.
Welcome to Genetic Mutations! 7x2WSY 7x2WSY.
 During replication (in DNA), an error may be made that causes changes in the mRNA and proteins made from that part of the DNA  These errors or changes.
Wake-up 1.Explain the difference between transcription and translation. (Hint: Think about what is made) 2.Explain difference between codon and anticodon.
Rate of mutations in the Human Genome A study published in Current Biology in 2009, shows that in total, we all carry new mutations in our DNA.
Mutations Csaba Bödör, Semmelweis University, 1 st Dept. of Pathology.
GENES, MUTATIONS & DISEASES: UNDERSTANDING THE ORIGINS OF GENETIC DISORDERS
Example 1 DNA Triplet mRNA Codon tRNA anticodon A U A T A U G C G
Fantasy Mutations Reality. Mutations: a permanent and heritable change in the nucleotide sequence of a gene. Are caused by mutagens (x-rays and UV light)
Living Environment Regents Review
The Secret Code of Life.
Catalyst What are the subunits of proteins?
Warm-Up (1/28) Answer the following questions, and explain in a complete sentence why each answer is correct. Name Date Period An organism with two copies.
LO: SWBAT explain how protein shape is determined and differentiate between the different types of mutations. DN: h/0 protein synthesis HW: Read pp.
Test on Genetics Tuesday (p. 5) Wednesday (p.1)
Protein Synthesis.
Mutations Mutations: changes in the genetic code that can lead to changes in the amino acid sequence and ultimately to the overall shape of the protein.
On Target? Do this on your Warm Up worksheet!
Warm-Up 12/8/2016 Which sequence is DNA, and which is RNA? How do you know? ATG GGA CTG CTC CAA AUG GGA CUG CUC CAA Sequence _____ is DNA because… Sequence.
Bellringer Three consecutive bases in mRNA are known as what?
Protein on Normal Red Blood Cells
Molecular Biology DNA Expression
Wishful Adaptation Paragraph
GENE MUTATIONS aka point mutations © 2016 Paul Billiet ODWS.
Do Now: Write the questions and answer them on page ___.
Catalyst Create a circle map about mutations. Mutations.
What is Transcription and who is involved?
Aim: How is protein shape determined?
Biology Mutations SNL Biology Copyright Pearson Prentice Hall.
Mutations In DNA By Mr. Guardiola.
MUTATIONS.
Biotechnology Gel Electrophoresis
Add to Table of Contents
Catalyst Create a circle map about mutations. Mutations.
NOTE SHEET 13 – Protein Synthesis
Mutations.
Bio Do Now Do you have the same DNA as the person sitting next to you?
Warm Up 3 2/5 Can DNA leave the nucleus?
Transcription and Translation
Changes in the nucleotide sequence of DNA or mRNA
Central Dogma and the Genetic Code
Normal DNA Strand DNA : TAC AAA GGA CGA GTA GTT TAA GCA AGA ATT
Biotechnology Gel Electrophoresis
Welcome to Genetic Mutations!
DNA, RNA, Amino Acids, Proteins, and Genes!.
MUTATIONS.
MUTATIONS.
Gene Protein Genome Proteome Genomics Proteomics.
DNA to proteins.
Protein Synthesis Genes: They’re all about ‘dem Proteins!
Protein Synthesis (Gene Expression) Notes
DNA (Gene) Mutations.
Gene Regulation and Mutations
Mutations Timothy G. Standish, Ph. D..
Presentation transcript:

Warm-Up (1/27) Answer the following questions, and explain in a complete sentence why each answer is correct. Name Date Period If a paramecium (a one-celled eukaryotic organism) is placed in a hypertonic environment, which of the following will occur? Water will diffuse into the paramecium. Water will diffuse out of the paramecium. Salt will be pumped out of the paramecium by the vacuole. Salt will be pumped into the paramecium by the vacuole. Draw a Punnett square showing a cross between a heterozygous person and a homozygous person for the A gene (“A” is the dominant allele; “a” is the recessive allele). What fraction of the offspring will show the dominant phenotype?

Mutations A DNA sequence: nucleus TAC CAC GTG GAC TGA GGA CTC CTC TTC Transcribe the mRNA sequence: TAC CAC GTG GAC TGA GGA CTC CTC TTC AUG GUG CAC CUG ACU CCU GAG GAG AAG

Mutations nucleus TAC CAC GTG GAC TGA GGA CTC CTC TTC AUG GUG CAC CUG ACU CCU GAG GAG AAG Translate the mRNA sequence into an protein: AUG GUG CAC CUG ACU CCU GAG GAG AAG Met Val His Leu Thr Pro Glu Glu Lys

Mutations A mutation is a change in DNA. TAC CAC GTG GAC TGA GGA CAC CTC TTC Transcribe the new mRNA. AUG GUG CAC CUG ACU CCU GUG GAG AAG Translate the new protein. Met Val His Leu Thr Pro Val Glu Lys

Mutations A mutation is a change in DNA. This changes the mRNA, which changes the protein. Normal Hemoglobin Protein Mutated Hemoglobin Protein Hemoglobin Video 1st 2 minutes

What do you see?

*you don’t have to write this down! Diseases that can occur with by a substitution or point mutation. Color blindness Cystic Fibrosis Cancer Tay-Sachs disease Sickle-cell anemia *you don’t have to write this down!

Mutations A mutation is a change in DNA. This changes the mRNA, which changes the protein. Substitution – replacing one nucleotide for another. Insertion – adding a nucleotide. Deletion – removing a nucleotide. old: ATG GAG GGA new: ATC GAG GGA old: ATG GAG GGA new: ATG CGA GGG A old: ATG GAG GGA new: ATG AGG GA

Carousel Activity 6 for a 70% 12 for a 100%

Closure Answer the following question in a complete sentence: Name Date Period If a DNA sequence is changed from TAC to TGC, how will the resulting amino acid change? Scale from 1-10