Early Philadelphia Neurology HISTORY OF Neurology Early Philadelphia Neurology Charles Mills, MD & Francis Xavier Dercum, MD Richard J. Barohn, MD The University of Kansas Medical Center

Charles Karsner Mills, MD 1845-1931 Born in Philadelphia Served as a soldier in the Civil War Univ. of Penn: 1869 – Medical School 1871 – PHD Initially practiced General Medicine Practiced devoted to nervous & mental diseases throughout Philadelphia Established Neuro Ward in 1887 at Philadelphia General Hospital “Old Blockley” Lecturer of Electrotherapeutics at Univ of Penn - 1877 Charles Karsner Mills, MD 1845-1931

Charles Karsner Mills, MD (1845-1931) Professor of Nervous & Mental Diseases, Philadelphia Polyclinic – 1883-1898 Clinical Professor of Nervous Diseases at Univ of Penn – 1901 Professor of Neurology at Univ of Penn – 1903 President of ANA – 1886 & 1924 Founder of Philadelphia Neurologic Society Founder of Philadelphia Post Graduate School of Neurology

Charles Karsner Mills MD 1845-1931 Textbook: The Nervous System and It’s Diseases (1898) He compared it to Gowers book! Dedicated to Weir Mitchell Emphasis of methods of neurological exam and localization Chapter on chemistry of nervous system Aphasia and localization papers – 1904 & 1915 Alcoholic neuropathy and psychic phenomena A case of unilateral progressive ascending paralysis, probably representing a new form of degenerative disease J Nerv Ment Dis 1900;27:195-200 Called “Mills Syndrome”: variant of ALS Descending Paralysis – 1906 Occlusion of the superior cerebellar artery – 1912 250 journal articles

The Nervous System and Its Diseases Charles Mills, MD; 1898

J Nerv Ment Dis 1900;27:195-200 JAMA. 1906;XLVII(20):1638-1645

Francis Xavier Dercum, MD 1858-1920 Born in Philadelphia U of Penn Med School 1877, PhD 1878 Private practice & also demonstrator at U Penn in histology /physiology Published on sensory organs, semicircular canals 1878/9 Prof of Nervous Disease Jefferson Med College in 1872 Chair of Nervous Disease, U Penn in 1884 Philadelphia General Hospital staff President of ANA in 1896 Late in life focused on psychiatry & endocrinology

Francis Xavier Dercum, MD 1858-1920 A Textbook on Nervous Diseases by American Authors - 1895 1st multi-authored neuro-text with only American Authors F.X. Dercum – Phil (6 chapters) General Considerations Neuorasthenia Arrested Development, Malformations Diseases of the Membranes, Sinuses , and Brain Tissue Cererbal Palsies of Childhood Paretic Dementia S Weir Mitchell- Phili Infirmary Nerv Dis (1) William Osler –Balt, Johns Hopkins (1) Diseases the Direct or Indirect result of Infection Charles Dana - NY, Bellevue Hosp (1) Hemorrhage, Embolism, and Thrombosis M. Allen Starr-NY Columbia (1) Tumors W.W. Keen- Phil, Infirmary Nerv Dis (1) Surgery of the Brain, Spinal cord, and nerves Charles Mills- Phil Phil Hosp (1) The Anatomy of the Cerebral Cortex and the Localization of its Function Frederick Peterson- NY, Columbia (3) Bulbar Palsy Multiple Cerebro-Spinal Sclerosis

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