Warm Up Bellwork: Set up your Journals for Notes Page:36 Title: Cancer EQ: What is cancer? What causes it and what effects can it have on an organism? If you did not get your definitions glued yesterday get a copy from me and glue on 35

DO NOT TOUCH THE COMPUTERS!! Bellwork: Set up your Journals for Notes Page:_______ Title: Cancer EQ: What is cancer? What causes it and what effects can it have on an organism? K What do I know about Cancer? W What do I want to know about Cancer? L What did I learn about Cancer today? *This will take the place of your summary. This is where you will answer the essential question for today. Copy this KWL chart into your notes and fill out the first two columns.

Due dates. Mark Calendars: All Classes: Unit 4 Notecards are Due next Wednesday Word and Definition only Pre-AP: Today is the last day to turn in Vocabulary Projects for any credit. After 4pm today the grade will remain a zero.

Today’s Standard: B.5D: The student will recognize that disruptions of the cell cycle lead to diseases such as cancer

How does cancer happen?

Cancer: disease caused by uncontrolled division of abnormal cells in a part of the body

Tumors cause damage to surrounding (healthy) tissue The abnormalities in the cells keep them from responding to normal checkpoints in the cell cycle. Abnormal cells will eventually form abnormal tissues called tumors. Tumor: a mass or swelling of a body part caused by an abnormal growth of tissue Tumors cause damage to surrounding (healthy) tissue

Pre-malignant - pre-cancerous Malignant - cancerous A tumor does not always mean cancer… Three Types of tumors: Benign - not cancerous Pre-malignant - pre-cancerous Malignant - cancerous In January 2012, Nguyen Duy Hai, a 32-year-old Vietnamese man underwent a 12-hour operation to remove a 200-pound tumor from his leg. Dr. McKay McKinnon, lead surgeon, had rated the success of the operation at just 50%. The surgery was a success. Do you want to see it? If not look away now….

How does cancer affect your body?

Metastasis- the process by which cancer cells get loose from the tumor and spread in the bloodstream to other locations in the body. For example, a patient may have started off with melanoma (skin cancer) which metastasized to their brain. The cancer cells that metastasize are the same as the original ones. If a lung cancer spreads to the liver, those cancer cells that grow in the liver are lung cancer cells which have acquired the ability to invade other organs.

What can cause cancer?

Cancer can be caused by… Tobacco use (lung, mouth and throat cancer) Radiation (genetic mutations) Viral infection (HPV can lead to cervical cancer in females).

For today… You will answer the first six questions while we watch the video AS A CLASS. You will complete the rest of the handout with your partner. This paper is due at the END of class TODAY!!! On cancer.org, under “Cancer Basics” click on “What is Cancer?” in the “Understanding Cancer” section to answer your questions.