Han-Pin Kuo, M.D., Ph.D., Chieh-Teng Yu, M.D. CHEST

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Alveolar Macrophage Subpopulations in Patients With Active Pulmonary Tuberculosis Han-Pin Kuo, M.D., Ph.D., Chieh-Teng Yu, M.D. CHEST Volume 104, Issue 6, Pages 1773-1778 (December 1993) DOI: 10.1378/chest.104.6.1773 Copyright © 1993 The American College of Chest Physicians Terms and Conditions

FIGURE 1 Repartition of alveolar macrophages of normal subjects (hatched bars, n = 10) and patients with TB (solid bars, n = 12) in the different Percoll gradient fractions: 1, <1.030 g/ml; 2, 1.030 to 1.040 g/ml; 3, 1.040 to 1.0.50 g/ml; 4, 1.050 to 1.070 g/ml; .5, >1.070 g/ml. Values are means ±SEM. Asterisk = p<0.05. CHEST 1993 104, 1773-1778DOI: (10.1378/chest.104.6.1773) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

FIGURE 2 Repartition of alveolar macrophages in smokers and nonsmokers either in patients with TB or in normal subjects in the different Percoli gradient fractions: 1, <1.030 g/ml; 2, 1.030 to 1.040 g/ml; 3, 1.040 to 1.050 g/ml; 4, 1.050 to 1.070 g/ml; 5, >1.070 g/ml. Values are means ± SEM. Asterisk = p<0.05; number sign = p<0.05 compared with corresponding smoker or nonsmoker subgroups in normal subjects, respectively. CHEST 1993 104, 1773-1778DOI: (10.1378/chest.104.6.1773) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

FIGURE 3 Correlation between the percentage of hypodense alveolar macrophages (< 1.030 g/ml) and the bacterial load of sputum in patients with TB (n = 12). A significant correlation is indicated. CHEST 1993 104, 1773-1778DOI: (10.1378/chest.104.6.1773) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

FIGURE 4 Correlation between the percentage of hypodense alveolar macrophages (<1.030 g/ml) and the disease extent on chest radiography in patients with TB (n = 12). A significant correlation is indicated. CHEST 1993 104, 1773-1778DOI: (10.1378/chest.104.6.1773) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

FIGURE 5 The CD4 to CD8 ratio of bronchoalveolar lavage in normal subjects (n = 10) and patients with TB (n = 12). Values are means ± SEM. Double asterisk = p<0.01 compared with normal subjects. CHEST 1993 104, 1773-1778DOI: (10.1378/chest.104.6.1773) Copyright © 1993 The American College of Chest Physicians Terms and Conditions