Table 4 Frequency of IRI3.2 alleles in individuals with different CCR5 genotypes From: The Δccr5 Mutation Conferring Protection Against HIV-1 in Caucasian Populations Has a Single and Recent Origin in Northeastern Europe Hum Mol Genet. 1998;7(3):399-406. doi:10.1093/hmg/7.3.399 Hum Mol Genet | © 1998 Oxford University Press

Table 3 Frequency of IRI3.1 alleles in individuals with different CCR5 genotypes From: The Δccr5 Mutation Conferring Protection Against HIV-1 in Caucasian Populations Has a Single and Recent Origin in Northeastern Europe Hum Mol Genet. 1998;7(3):399-406. doi:10.1093/hmg/7.3.399 Hum Mol Genet | © 1998 Oxford University Press

Table 2 Observed frequency of IRI3 Table 2 Observed frequency of IRI3.1 alleles in CCR5/CCR5 homozygotes from different populations From: The Δccr5 Mutation Conferring Protection Against HIV-1 in Caucasian Populations Has a Single and Recent Origin in Northeastern Europe Hum Mol Genet. 1998;7(3):399-406. doi:10.1093/hmg/7.3.399 Hum Mol Genet | © 1998 Oxford University Press

Figure 2 PCR amplification of the IRI3. 1 and IRI3. 2 microsatellites Figure 2 PCR amplification of the IRI3.1 and IRI3.2 microsatellites. Genomic fragments of ∼150 bp containing the IRI3.1 or IRI3.2 microsatellites were amplified by PCR and separated on a denaturing polyacrylamide gel. A set of samples representative of the three CCR5 genotypes (CCR5/CCR5, CCR5/Δccr5 and Δccr5/Δccr5) are shown. The microsatellite alleles are identified for each individual by the number of dinucleotide repeats, relative to IRI3.1-0 and IRI3.2-0. From: The Δccr5 Mutation Conferring Protection Against HIV-1 in Caucasian Populations Has a Single and Recent Origin in Northeastern Europe Hum Mol Genet. 1998;7(3):399-406. doi:10.1093/hmg/7.3.399 Hum Mol Genet | © 1998 Oxford University Press

Figure 1 Frequency of the Δccr5 allele in European populations Figure 1 Frequency of the Δccr5 allele in European populations. Schematic map of Europe indicating the frequency (in percentage) of the CCR5 mutant allele Δccr5 in the various populations tested in this study. The samples originated from the regions of Oslo (Norway), Umea and Lapland (Sweden), Helsinki (Finland), Saransk (Mordvinia), Moscow (Russia), Copenhagen (Denmark), Vilnius (Lithuania), Brest and Montpellier (France), Brussels (Belgium), Milan and Cagliari (Italy), Budapest (Hungary), Lisbon (Portugal), Espinardo and Bilbao (Spain) and Ankara (Turkey). From: The Δccr5 Mutation Conferring Protection Against HIV-1 in Caucasian Populations Has a Single and Recent Origin in Northeastern Europe Hum Mol Genet. 1998;7(3):399-406. doi:10.1093/hmg/7.3.399 Hum Mol Genet | © 1998 Oxford University Press

Table 1 Distribution of CCR5 genotypes and frequency of the Δccr5 allele in European populations From: The Δccr5 Mutation Conferring Protection Against HIV-1 in Caucasian Populations Has a Single and Recent Origin in Northeastern Europe Hum Mol Genet. 1998;7(3):399-406. doi:10.1093/hmg/7.3.399 Hum Mol Genet | © 1998 Oxford University Press