Volume 120, Issue 4, Pages (March 2001)

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Volume 120, Issue 4, Pages 799-805 (March 2001) Efficacy and tolerability of racecadotril in acute diarrhea in children Jean Pierre Cézard, Jean François Duhamel, Martine Meyer, Isabelle Pharaon, Marc Bellaiche, Chantal Maurage, Jean Louis Ginies, Jean Michel Vaillant, Jean Philippe Girardet, Thierry Lamireau, Alain Poujol, Alain Morali, Jacques Sarles, Jean Pierre Olives, Caroline Whately–Smith, Jeanne Marie Lecomte Gastroenterology Volume 120, Issue 4, Pages 799-805 (March 2001) DOI: 10.1053/gast.2001.22544 Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 1 Mean (±SEM) stool output during the first 48 hours of treatment for the full data set and the per-protocol population (covariance analysis). **P = 0.009; ***P = 0.001. Gastroenterology 2001 120, 799-805DOI: (10.1053/gast.2001.22544) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 2 Mean (±SEM) stool output during the first 48 hours of treatment for rotavirus-positive and rotavirus-negative patients (per-protocol population). Treatment effect P = 0.001. Interaction rotavirus × treatment, P = 0.500. Gastroenterology 2001 120, 799-805DOI: (10.1053/gast.2001.22544) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 3 Mean (±SEM) stool output during the first 24 hours of treatment for the full data set and the per-protocol population. *P = 0.025. **P = 0.015. Gastroenterology 2001 120, 799-805DOI: (10.1053/gast.2001.22544) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 4 Time to recovery in rotavirus-positive patients receiving racecadotril (n = 32) and placebo (n = 35). P = 0.02. Gastroenterology 2001 120, 799-805DOI: (10.1053/gast.2001.22544) Copyright © 2001 American Gastroenterological Association Terms and Conditions