Pharmacy Technician Compounding

Compounding Extemporaneous compounding is the on-demand preparation of a drug product according to a physician’s prescription to meet the unique needs of an individual patient. Definition: the preparation, mixing, assembling, packing and labeling of a drug device Compounding is regulated by the State Boards of Pharmacy & the US Pharmacopeia

Reasons for Compounding Pediatric patients requiring diluted adult strengths of drugs Patients needing an oral solution or suspension of a product that is only available in another form Patients with sensitivity to dyes, preservatives or flavoring agents found in commercial formulations

Reasons continued… Dermatological formulations with fortified or diluted concentrations of commercially available products Specialized dosages for therapeutic drug monitoring Care for hospice patients in pain management Compounding for animals

Technicians are increasingly involved in compounding, under supervision of a pharmacist.

Compounding Regulations Personnel Facilities & Equipment Ingredient Standards Quality Assurance and Quality Control

Packaging and storing Documentation & Record Keeping

Compounding Considerations Is there a commercial product available? Is the pharmacist qualified to compound? Determine a preliminary procedure.

MEASURE MIX MOLD PACKAGE 4 step process MEASURE MIX MOLD PACKAGE

Equipment Balance Spatulas Weighing papers & Weighing Boats Electronic, Class Aa Spatulas Weighing papers & Weighing Boats Mortars and Pestles

Volumetric (liquid) Equipment Graduated Cylinders Volumetric Flasks Pipets Single volume, calibrated Syringes Oral Droppers

Mixing Solids & Semisolids Mixing Tablets Ointment Slabs Levigation Hot plates

Compounding Principles for Dosage Forms Aqueous solutions Nonaqeuous solutions Suspensions “Flavor” Emulsion Ointment (2 types) Suppository bases Capsules