Polymyositis Associated With Severe Interstitial Lung Disease Bakewell Catherine J. , MD, Raghu Ganesh , MD  CHEST  Volume 139, Issue 2, Pages 441-443 (February 2011) DOI: 10.1378/chest.10-0360 Copyright © 2011 The American College of Chest Physicians Terms and Conditions

Figure 1 Postero-anterior chest radiograph at initial presentation demonstrating irregular streaky opacities consistent with interstitial fibrosis at the lung bases bilaterally. CHEST 2011 139, 441-443DOI: (10.1378/chest.10-0360) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

Figure 2 A, Initial high-resolution CT (HRCT) scan of the chest demonstrating interstitial pneumonia with ground glass opacification, mild intralobular septal thickening, and subtle honeycombing, with subpleural sparing consistent with features of nonspecific interstitial pneumonia. B, HRCT scan 20 months later demonstrates complete resolution of previously noted changes. CHEST 2011 139, 441-443DOI: (10.1378/chest.10-0360) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

Figure 3 Histopathologic examination of transbronchial lung biopsy specimen. A, Plugs of granulation tissue characteristic of organizing pneumonia. A mechanically crushed inflammatory infiltrate is also present (hematoxylin and eosin stain, original magnification × 10). B, Mostly compressed alveolar lung tissue with mild lymphocytic inflammation in the top of the image (hematoxylin and eosin stain, original magnification × 20). Together the images show cellular (lymphocytic) interstitial pneumonitis with organizing pneumonia. CHEST 2011 139, 441-443DOI: (10.1378/chest.10-0360) Copyright © 2011 The American College of Chest Physicians Terms and Conditions