Peter K. Smith, MD, Robert M. Califf, MD, Robert H

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Presentation transcript:

Selection of Surgical or Percutaneous Coronary Intervention Provides Differential Longevity Benefit Peter K. Smith, MD, Robert M. Califf, MD, Robert H. Tuttle, MSPH, Linda K. Shaw, MHS, Kerry L. Lee, PhD, Elizabeth R. Delong, PhD, R. Eric Lilly, MD, Michael H. Sketch, MD, Eric D. Peterson, MD, Robert H. Jones, MD The Annals of Thoracic Surgery Volume 82, Issue 4, Pages 1420-1429 (October 2006) DOI: 10.1016/j.athoracsur.2006.04.044 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Initial treatment selection according to coronary artery disease severity and era. Black bars = medical therapy; white bars = percutaneous intervention; triangles = coronary artery bypass grafting. The Annals of Thoracic Surgery 2006 82, 1420-1429DOI: (10.1016/j.athoracsur.2006.04.044) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Cumulative proportion of treatment crossovers across study period. (CABG = coronary artery bypass grafting; MED = medical therapy; PCI = percutaneous intervention.) The Annals of Thoracic Surgery 2006 82, 1420-1429DOI: (10.1016/j.athoracsur.2006.04.044) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Risk of all-cause death. Solid line = medical therapy; varied length dashed line = percutaneous intervention; dashed line = coronary artery bypass grafting. The Annals of Thoracic Surgery 2006 82, 1420-1429DOI: (10.1016/j.athoracsur.2006.04.044) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Adjusted survival rates according to initial treatment strategy. (CABG = coronary artery bypass grafting; MED = medical therapy; PCI = percutaneous intervention.) The Annals of Thoracic Surgery 2006 82, 1420-1429DOI: (10.1016/j.athoracsur.2006.04.044) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Impact of coronary artery disease (CAD) severity on adjusted survival: revascularization versus medical therapy (MED). The Annals of Thoracic Surgery 2006 82, 1420-1429DOI: (10.1016/j.athoracsur.2006.04.044) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Adjusted survival differences versus initial treatment selection (1986–2000). Degree of coronary artery disease: black bar = low severity; gray bar = intermediate severity; white bar = high severity; *p < 0.05. The Annals of Thoracic Surgery 2006 82, 1420-1429DOI: (10.1016/j.athoracsur.2006.04.044) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 7 Adjusted survival differences for coronary artery bypass grafting (CABG) versus percutaneous intervention (PCI) according to era of initial treatment. (CAD = coronary artery disease.) The Annals of Thoracic Surgery 2006 82, 1420-1429DOI: (10.1016/j.athoracsur.2006.04.044) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions