Safety of coronary CT angiography and functional testing for stable chest pain in the PROMISE trial: A randomized comparison of test complications, incidental.

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Presentation transcript:

Safety of coronary CT angiography and functional testing for stable chest pain in the PROMISE trial: A randomized comparison of test complications, incidental findings, and radiation dose  Michael T. Lu, Pamela S. Douglas, James E. Udelson, Elizabeth Adami, Brian B. Ghoshhajra, Michael H. Picard, Rhonda Roberts, Kerry L. Lee, Andrew J. Einstein, Daniel B. Mark, Eric J. Velazquez, William Carter, Michael Ridner, Hussein R. Al-Khalidi, Udo Hoffmann  Journal of Cardiovascular Computed Tomography  Volume 11, Issue 5, Pages 373-382 (September 2017) DOI: 10.1016/j.jcct.2017.08.005 Copyright © 2017 Society of Cardiovascular Computed Tomography Terms and Conditions

Fig. 1 (A) Main analysis comparing test complications, incidental findings, and radiation dose between computed tomography angiography (CTA) and functional testing, as tested. (B) Sub-analysis with randomization stratified to the subgroup of patients whose physician intended to refer for nuclear stress testing if randomized to the functional arm. Radiation dose and patient, technology, and site factors associated with dose were compared for CTA versus nuclear stress testing. CAD indicates coronary artery disease; CT, computed tomography; ETT, exercise tolerance test; ICA, invasive coronary angiography; PROMISE, PROspective Multicenter Imaging Study for Evaluation of Chest Pain. Journal of Cardiovascular Computed Tomography 2017 11, 373-382DOI: (10.1016/j.jcct.2017.08.005) Copyright © 2017 Society of Cardiovascular Computed Tomography Terms and Conditions

Fig. 2 Estimated effective radiation dose in the subgroup intended for nuclear stress testing prior to randomization. Dark blue bars indicate overlap between computed tomography angiography (CTA) and nuclear stress testing radiation dose. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.) Journal of Cardiovascular Computed Tomography 2017 11, 373-382DOI: (10.1016/j.jcct.2017.08.005) Copyright © 2017 Society of Cardiovascular Computed Tomography Terms and Conditions