Volume 85, Issue 10, Pages (October 2014)

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Presentation transcript:

Volume 85, Issue 10, Pages 1387-1393 (October 2014) A pilot study of cerebrovascular reactivity autoregulation after pediatric cardiac arrest Jennifer K. Lee, Ken M. Brady, Shang-En Chung, Jacky M. Jennings, Emmett E. Whitaker, Devon Aganga, Ronald B. Easley, Kerry Heitmiller, Jessica L. Jamrogowicz, Abby C. Larson, Jeong-Hoo Lee, Lori C. Jordan, Charles W. Hogue, Christoph U. Lehmann, Mela M. Bembea, Elizabeth A. Hunt, Raymond C. Koehler, Donald H. Shaffner Resuscitation Volume 85, Issue 10, Pages 1387-1393 (October 2014) DOI: 10.1016/j.resuscitation.2014.07.006 Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Hemoglobin volume index (HVx) and mean arterial blood pressure (MAP) monitoring in two infants during the first 48h after return of circulation. (A, B) Patient 28 was 16 days old, had a change in the Pediatric Cerebral Performance Category score (ΔPCPC) of 0, and did not require a tracheostomy or gastrostomy. HVx showed an optimal MAP at 40mmHg (nadir of HVx; arrow). (B) This patient spent 3% of the monitoring period with blood pressure below optimal MAP. (C, D) Patient 3 was 8 days old, had a ΔPCPC of 2, and received a new gastrostomy. HVx showed an optimal MAP at 45mmHg (arrow). (D) This patient spent 67% of the monitoring period with blood pressure below optimal MAP. Resuscitation 2014 85, 1387-1393DOI: (10.1016/j.resuscitation.2014.07.006) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Optimal mean arterial blood pressure (MAP) was identified during the first 48h after return of circulation in 29 children. (A) Optimal MAP increased with age. The discontinuous x-axis emphasizes the inter-patient variability in optimal MAP among patients of similar age. (B) Optimal MAP and the 50th percentile for MAP were mismatched in many children. Each circle represents one patient. Resuscitation 2014 85, 1387-1393DOI: (10.1016/j.resuscitation.2014.07.006) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions