Energy for Muscular Activity
Learning Objectives: To develop an awareness of the basic chemical process that the body uses to produce energy in the muscles To develop an understanding of the body’s three main energy systems To introduce the effect of training and exercise on the energy systems
The Chemistry of Energy Production Energy in the human body is derived from the breakdown of complex nutrients like carbohydrates, fats, and proteins. The end result of this breakdown is production of the adenosine triphosphate (ATP) molecule. ATP provides energy necessary for body functions Breakdown of Energy currency Biochemical processes Carbohydrates Fats Proteins Muscular Work Digesting Food Thermoregulation ATP
ATP Cycle Overview a) ATP breakdown b) Phosphorylation c) ATP resynthesis
a) ATP breakdown (ATP turnover) ADP H2O + Energy + P + 1. Hydrolysis of the unstable phosphate groups of ATP molecule by H2O 2. Phosphate molecule (P) is released from ATP (ATP ADP) 3. Energy is released (used for muscle contraction)
b) Phosphorylation Molecule P + Energy for muscle contraction 1. Energy released by ATP turnover can be used by body when a free P group is transferred to another molecule like ADP (phosphorylation)
c) ATP resynthesis ADP ATP Energy P + P + Initial stores of ATP in the muscles are used up very quickly and ATP must be regenerated 2. ATP is formed by recombination of ADP and P 3. Regeneration of ATP requires energy (from breakdown of food molecules)
The Energy Systems b) the anaerobic glycolytic system the high energy phosphate system b) the anaerobic glycolytic system c) the aerobic oxidative system
The Roles of the Three Energy Systems in Competitive Sport
1. The High Energy Phosphate System
The High Energy Phosphate System Overview Primary energy source: Duration of activity: Sporting events: Advantages: Limiting factors: Stored ATP, CP 7-12 s Weight lifting, high jump, long jump, 100m run, 25m swim Produce very large amount of energy in a short amount of time Initial concentration of high energy phosphates (ATP, PC)
High Energy Phosphate System
Training the High Energy Phosphate System a) Interval training: - 20% increase in CP (creatine phosphate) stores - no change in ATP stores - increase in ATP function (ATP -> ADP+P) b) Sprint training: - increase in CP stores up to 40% - 100% increase in resting ATP stores
2. The Anaerobic Glycolytic System 0-7 min
The Anaerobic Glycolytic System Overview Primary energy source: Duration of activity: Sporting events: Advantages: Limiting factors: Stored glycogen, blood glucose 12 s – 3 min Lactic acid build up 800m run, 200m swim, downhill ski racing, 1500 speed skating Ability to produce energy under conditions of inadequate oxygen
The Anaerobic Glycolytic System
anaerobic process (in the absence of oxygen) Glycolysis A biochemical process that releases energy in the form of ATP from glycogen and glucose anaerobic process (in the absence of oxygen) The products of glycolysis (per molecule of glycogen): - 2 molecules of ATP - 2 molecules of pyruvic acid The by-product of glycolysis (per molecule of glycogen): - 2 molecules of lactic acid
The highly complex metabolic pathways of glycolysis ) The highly complex metabolic pathways of glycolysis
Anaerobic Threshold The exercise intensity at which lactic acid begins to accumulate within the blood The point during exercise where the person begins to feel discomfort and burning sensations in their muscles Lactic acid is used to store pyruvate and hydrogen ions until they can be processed by the aerobic system
The Anaerobic Glycolytic System cont. Starts when: the reserves of high energy phosphate compounds fall to a low level the rate of glycolysis is high and there is a build up of pyruvic acid
Substrates for the anaerobic energy system The primary source of substrates is carbohydrate Carbohydrates: primary dietary source of glucose primary energy fuels for brain, muscles, heart, liver
Carbohydrate breakdown and storage Complex Carbohydrates Digestive system Glucose Blood Stream Gluconeogenesis Circulation of glucose around body Glucose stored in blood Glycogen Glycogen stored in muscle or liver
Effect of Training on the Anaerobic Glycolytic System Rate of lactic acid threshold is increased in the trained individual This rate can be decreased by: a) reducing the rate of lactate production - increase in the effectiveness of the aerobic oxidative system b) increasing the rate of lactate elimination - increased rate of lactic acid diffusion from active muscles - increased muscle blood flow - increased ability to metabolize lactate in the heart, liver and in non-working muscle
3. The Aerobic Oxidative System 7-12 min
The Aerobic Oxidative System Overview Primary energy source: Duration of activity: Sporting events: Advantages: Limiting factors: Glycogen, glucose, fats, proteins > 3 min Lung function, max.blood flow, oxygen availability, excess. energy demands Walking, jogging, swimming, walking up stairs Large output of energy over a long period of time, removal of lactic acid
Aerobic Oxidative System
The Aerobic Oxidative System The most important energy system in the human body Blood lactate levels remain relatively low (3-6mmol/L bl) Primary source of energy (70-95%) for exercise lasting longer than 10 minutes provided that: a) working muscles have sufficient mitochondria to meet energy requirements b) sufficient oxygen is supplied to the mitochondria c) enzymes or intermediate products do not limit the Kreb’s cycle Primary source of energy for the exercise that is performed at an intensity lower than that of the anaerobic oxidative system
The Oxidative Phosphorylation System Two Pathways: Krebs Cycle & Electron Transport Chain Biochemical process used to resynthesize ATP by combining ADP and P in the presence of oxygen Takes place in mitochondrion (contains enzymes, co-enzymes) Energy yield from 1 molecule of glucose is 36 ATP molecules Energy yield from 1 molecule of fat up to 169 ATP molecules By-products of this reaction: carbon dioxide, water
Cori Cycle Lactic acid is taken to the liver to be metabolized back into pyruvic acid and then glucose
The Power Of The Aerobic System Evaluated by measuring the maximal volume of oxygen that can be consumed per kilogram of mass in a given amount of time This measure is called aerobic power or VO2 max (ml/min/kg)
The Substrates for the Aerobic System Carbohydrates ( glycogen and glucose) and fats (triglycerides and fatty acids) Fats: found in dairy products, meats, table fats, nuts, and some vegetables body’s largest store of energy, cushion the vital organs, protect the body from cold, and serve to transport vitamins each gram of fat contains 9 calories of energy
Effect of Training on Aerobic Systems Endurance training is the most effective method (long duration several times per week): - increases vascularization within muscles - increases number and size of mitochondria within the muscle fibres - increases the activity of enzymes (Krebs cycle) - preferential use of fats over glycogen during exercise Endurance training increases the max aerobic power of a sedentary individual by 15-25% regardless of age An older individual adapts more slowly
Summary of the three energy systems
The Role of Three Energy Systems During an All-out Exercise Activity of Different Duration
Success Criteria: 1. What are the differences between the 3 energy systems? 2. List one advantage and one disadvantage of each of the 3 energy systems. 3. Give an example of three activities or sports that use each of (a) the high energy phosphate system, (b) the anaerobic glycolytic system, and (c) the aerobic oxidative system as their primary source of energy (one sport for each energy system). 4. What is the most important source of fuel in the body for all types of energy production - a substance also known as the energy currency of the body? 5. Define ATP turnover and ATP resynthesis. 6. Describe how each of the three energy systems could be trained most efficiently.