Dr. Nadav Amdursky Faculty of Chemistry, Technion – Israel Institute of Technology, Israel Expertise in: The formation of various protein-based microscopic (fibrils, tubes, spheres) and macroscopic structures (hydrogels, membranes, mats) and the chemical incorporation of external cofactors to them, in order to induce new optical and electronic properties to them. Following photo-induced proton transfer and electron transfer by steady-state fluorescence and time-resolved ultra-fast fluorescence (laser amplifier + OPA). Capable of exciting the sample in the 230 – 800 nm range, and follow the fluorescence in the 300-850 nm range. Capable of following fluorescence lifetimes from 50 fs up to phosphorescence (hundreds of μs). We have plans in the near future to upgrade our laser system to include also transient absorption capabilities in the mid-IR. Making ‘bioelectronic’ devices to study electric-field induced electron conduction and proton conduction from across a single layer of proteins to macroscopic junctions, by both DC current-voltage and AC impedance techniques, in a controlled environment in terms of temperature (-40°C - +120°C), humidity (0-100% RH), pressure (1x10-5 – 5 atm) and presence of gas mixtures. Google Scholar profile: https://scholar.google.co.il/citations?user=S6te4pYAAAAJ&hl=en Selected papers: http://onlinelibrary.wiley.com/doi/10.1002/adma.201505337/abstract http://onlinelibrary.wiley.com/doi/10.1002/cplu.201500121/full http://pubs.rsc.org/-/content/articlehtml/2015/cp/c5cp05548b http://pubs.acs.org/doi/abs/10.1021/jp509153r http://onlinelibrary.wiley.com/doi/10.1002/adma.201402304/full

Expected benefits and activities during participation in BIONECA: Share experience and state-of-the-art techniques for the formation of soft materials that can be chemically modified, and can be used for tissue engineering for both cardiology and neurology. Discuss the use of charge conducting (ions, protons, electrons) scaffolds for tissue engineering applications in the field of cardiology and neurology. Discuss my own results and the results present in the literature in this context. My main scientific question to be answered in BIONECA: in light of recent results of the use of conductive substrates (for cardiology and neurology), what is the molecular charge transport mechanism between the scaffold and the cellular tissue? And can this type of scaffold can be used in a smart way, i.e., to electrically activate it during the tissue differentiation and formation process. If the previous question can be answered or hypothesized, I would like to collaborate in both doing research to probe the hypotheses and to write a review about the subject. Foreseen maximum contribution: in WG1