Dynamic renal blood flow measurement by positron emission tomography in patients with CRF Laurent Juillard, MD, PhD, Marc F. Janier, MD, PhD, Denis Fouque, MD, PhD, Luc Cinotti, MD, Nora Maakel, MD, Didier Le Bars, PD, PhD, Paul Y. Barthez, DVM, PhD, Nicole Pozet, MD, Maurice Laville, MD American Journal of Kidney Diseases Volume 40, Issue 5, Pages 947-954 (November 2002) DOI: 10.1053/ajkd.2002.36325 Copyright © 2002 National Kidney Foundation, Inc Terms and Conditions
Fig. 1 Renal PET static images using H215O. Each image represents a transversal slice in which high activity corresponds to the cortex (orange arrow on image 2) and higher activity to the aorta (red arrow on image 2). Orientation: Ant = up, Right = left. The upper left image represents the subdiaphragm slice, the lower right image, the inferior slice. Color scale shown on left side of the image. American Journal of Kidney Diseases 2002 40, 947-954DOI: (10.1053/ajkd.2002.36325) Copyright © 2002 National Kidney Foundation, Inc Terms and Conditions
Fig. 2 Examples of aortic (dashed line) and tissue (solid lines) PET TACs from one patient. Input function (aortic PET TAC) represents the evolution in time of the mean of activity measured in the aortic ROI. Tissue function (kidney PET TACs, baseline [K bl], and periods 1 [K P1], 2 [K P2], 3 [K P3], and 4 [K P4]) represents the evolution in time of the mean of activity measured in the two kidneys ROI. American Journal of Kidney Diseases 2002 40, 947-954DOI: (10.1053/ajkd.2002.36325) Copyright © 2002 National Kidney Foundation, Inc Terms and Conditions
Fig. 3 Evolution of relative PET-RBF (in percent) 5, 40, 80, and 120 minutes after quinaprilat injection, and PAH-ERPF (percent) during periods P1, P2, P3, and P4. *P ≤ 0.05. Abbreviation: BL, baseline. American Journal of Kidney Diseases 2002 40, 947-954DOI: (10.1053/ajkd.2002.36325) Copyright © 2002 National Kidney Foundation, Inc Terms and Conditions
Fig. 4 Correlation (r = 0.81; P ≤ 0.001) between PET-RBF and PAH-ERPF. American Journal of Kidney Diseases 2002 40, 947-954DOI: (10.1053/ajkd.2002.36325) Copyright © 2002 National Kidney Foundation, Inc Terms and Conditions