Copyright © 2015 by the American Osteopathic Association. From: Application of Incretin Mimetics and Dipeptidyl Peptidase IV Inhibitors in Managing Type 2 Diabetes Mellitus J Am Osteopath Assoc. 2007;107(suppl_3):S10-S16. Figure Legend: Comparison of the administration routes and physiologic effects of the incretin modulators—incretin mimetics and dipeptidyl peptidase IV inhibitors—in patients with type 2 diabetes mellitus based on compilation of overall incretin studies by the National Diabetes Education Initiative (NDEI). *Data from animal studies. Abbreviations: DPP-IV, dipeptidyl peptidase IV; GLP-1, glucagon-like peptide 1. (Reprinted with permission from the NDEI.) Date of download: 10/6/2017 Copyright © 2015 by the American Osteopathic Association. All rights reserved.