Aigul Zagidullina Arkadiy Aleksandrov , Bulat Aznabaev

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Aigul Zagidullina Arkadiy Aleksandrov , Bulat Aznabaev OUR EXPERIENCE OF USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN PRIMARY OPEN ANGLE GLAUCOMA DIAGNOSTICS Aigul Zagidullina Arkadiy Aleksandrov , Bulat Aznabaev Ophthalmology, Federal Bashkir State Medical University of the Ministry of Health RF, Ufa, Russian Federation Purpose Results To examine the state of the microcirculation of the optic nerve in patients with early and advanced stages of POAG. Patients with early POAG had a decrease in blood flow index at the optic nerve head (ONH) level, which averaged 0.138 ± 0.024, which was 5.5% lower than in the control group (p <0.05). The blood flow index at the radial peripapillary capillaries (RPC) level averaged 0.055 ± 0.03, which was 15.4% lower than in the control group (p <0.05); decrease in the blood flow index at the Choroid/Disc level, which averaged 0.134 ± 0.026, which was 2.2% lower than the comparable index in the control group (p <0.05). It was revealed a decrease of blood flow index at the ONH level in patients with advanced stage of POAG, which averaged 0.132 ± 0.039, which was 9.6% lower than in the control group and 4.4% lower than in the group of patients with early POAG (p <0.05). It was observed a decrease of blood flow index at the RPC level, which amounted to 0.045 ± 0.029 (p <0.05). The blood flow index at the Choroid/Disc level averaged 0.125 ± 0.029 (p <0.05). Materials and methods It was examined 210 people: 120 patients with POAG (65 people at an early stage, 55 – at advanced); aged from 46 to 78 years (66.7 ± 8.6). The control group (normal) included 90 somatically healthy persons without ophthalmopathology; aged from 45 to 74 years (61.2 ± 7.8). The groups were matched by age and sex. The study of the optic nerve microcirculation was carried out with Optical coherence tomography angiography using SSADA algorithm by the spectral optical coherence tomographic scanner Optovue RTVue Avanti XR with the function AngioVue (USA). Normal ONH blood flow index ONH = 0,156 Normal ONH 0,156 blood flow index ONH = 0,138 Glaucoma 0,139 Conclusions Thus, the blood flow index, as a quantitative parameter enables to assess non-invasively the state of optic nerve micro-circulation and identify different-level disorders in patients with POAG, moreover the changes are revealed at initial stage of the disease.