Patients who had reported experiencing symptoms in the previous 7 days were asked during what times of the day the symptoms were most troublesome. a) Breathlessness, n = 1,769; b) phlegm, n = 1,551; c) cough, n = 1,433; d) wheezing, n = 1,018; and e) chest ... Patients who had reported experiencing symptoms in the previous 7 days were asked during what times of the day the symptoms were most troublesome. a) Breathlessness, n = 1,769; b) phlegm, n = 1,551; c) cough, n = 1,433; d) wheezing, n = 1,018; and e) chest tightness, n = 690. R. Kessler et al. Eur Respir J 2011;37:264-272 ©2011 by European Respiratory Society