Infant Growth after Preterm Birth and Neurocognitive Abilities in Young Adulthood Sara Sammallahti, MA, Riikka Pyhälä, PhD, Marius Lahti, PhD, Jari Lahti,

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Presentation transcript:

Infant Growth after Preterm Birth and Neurocognitive Abilities in Young Adulthood Sara Sammallahti, MA, Riikka Pyhälä, PhD, Marius Lahti, PhD, Jari Lahti, PhD, Anu-Katriina Pesonen, PhD, Kati Heinonen, PhD, Petteri Hovi, MD, PhD, Johan G. Eriksson, MD, PhD, Sonja Strang-Karlsson, MD, PhD, Sture Andersson, MD, PhD, Anna-Liisa Järvenpää, MD, PhD, Eero Kajantie, MD, PhD, Katri Räikkönen, PhD The Journal of Pediatrics Volume 165, Issue 6, Pages 1109-1115.e3 (December 2014) DOI: 10.1016/j.jpeds.2014.08.028 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 2 Change in general neurocognitive abilities (in SD units) in young adulthood per 1 SD faster growth from birth to term equivalent age and from term to 12 months CA in individuals with VLBW (<1500 g). All associations were adjusted for gestational age, sex, time period between closest true measurement point and age at neurocognitive testing, and highest education of a parent. All associations were adjusted for gestational age, sex, time period between closest true measurement point and age at neurocognitive testing, highest education of a parent, and neonatal complications and illnesses (septicemia, bronchopulmonary dysplasia, indomethacin treatment, surgery because of patent ductus arteriosus, blood exchange transfusion because of hyperbilirubinemia, intraventricular hemorrhage, and duration of ventilator treatment). The Journal of Pediatrics 2014 165, 1109-1115.e3DOI: (10.1016/j.jpeds.2014.08.028) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 3 Change in executive functioning, attention, and visual memory (in SD units) in young adulthood per one SD faster growth from birth to term and from term to 12 months CA in individuals with VLBW (<1500 g). All associations were adjusted for gestational age, sex, time period between closest true measurement point and age at neurocognitive testing, and highest education of a parent. All associations were adjusted for gestational age, sex, time period between closest true measurement point and age at neurocognitive testing, highest education of a parent, and neonatal complications and illnesses (septicemia, bronchopulmonary dysplasia, indomethacin treatment, surgery because of patent ductus arteriosus, blood exchange transfusion because of hyperbilirubinemia, intraventricular hemorrhage, and duration of ventilator treatment). The Journal of Pediatrics 2014 165, 1109-1115.e3DOI: (10.1016/j.jpeds.2014.08.028) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Change in individual neurocognitive test scores (in SD units) in young adulthood per one SD faster growth from birth to term and from term to 12 months CA in individuals with VLBW (<1500 g). Adjusted for gestational age, sex, time period between closest true measurement point. P < .05 after also controlling for duration of ventilator treatment, septicemia, bronchopulmonary dysplasia, received indomethacin, surgery because of patent ductus arteriosus, intraventricular hemorrhage, and blood exchange transfusion because of hyperbilirubinemia. CPT, Conners' Continuous Performance Test; Effect size, SD change in test score; ROCF, Rey-Osterrieth Complex Figure; Stroop, Stroop test; TMT, Trail Making Test; WAIS-III, Wechsler Adult Intelligence Scale III. The Journal of Pediatrics 2014 165, 1109-1115.e3DOI: (10.1016/j.jpeds.2014.08.028) Copyright © 2014 Elsevier Inc. Terms and Conditions