P. Coleridge-Smith, C. Lok, A.-A. Ramelet 

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Presentation transcript:

Venous Leg Ulcer: A Meta-analysis of Adjunctive Therapy with Micronized Purified Flavonoid Fraction  P. Coleridge-Smith, C. Lok, A.-A. Ramelet  European Journal of Vascular and Endovascular Surgery  Volume 30, Issue 2, Pages 198-208 (August 2005) DOI: 10.1016/j.ejvs.2005.04.017 Copyright © 2005 Terms and Conditions

Fig. 1 Reduction of the relative risk of ulcer healing at 2 months in trials comparing micronized purified flavonoid fraction (MPFF) with control. O, observed number of healed patients; N, total number of patients; E, expected number of healed patients; V, variance; CI, confidence interval. European Journal of Vascular and Endovascular Surgery 2005 30, 198-208DOI: (10.1016/j.ejvs.2005.04.017) Copyright © 2005 Terms and Conditions

Fig. 2 Life-table analysis with cumulative percentage of patients in whom the ulcer healed completely. Comparison in cumulative healing rates between the micronized purified flavonoid fraction group (solid line) and the control group (broken line). Median time to healing: MPFF, 16.14 weeks; control, 21.30 weeks. Hazard ratio, 1.33. European Journal of Vascular and Endovascular Surgery 2005 30, 198-208DOI: (10.1016/j.ejvs.2005.04.017) Copyright © 2005 Terms and Conditions