C. Transgenic mice that express the CaMKII-Asp286 kinase and receive doxycycline perform as well as wild-type mice in learning the Barnes maze task (approximately.

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03-05 W. W. Norton 02-11ab Adapted from Kandel, E.R. Schwartz, J.H., and Jessell, T.M. (Eds.), Principles of Neural Science, 3rd.
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Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Memory and behavior: a second generation of genetically modified mice
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
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C. Transgenic mice that express the CaMKII-Asp286 kinase and receive doxycycline perform as well as wild-type mice in learning the Barnes maze task (approximately 65% of animals learn the task), whereas transgenic mice without the doxycycline (in which the kinase is highly expressed) do not learn the task. Source: Prefrontal Cortex, Hippocampus, and the Biology of Explicit Memory Storage, Principles of Neural Science, Fifth Editon Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available at: https://neurology.mhmedical.com/DownloadImage.aspx?image=/data/books/1049/kan_ch67_f014.png&sec=59149464&BookID=1049&ChapterSecID=59138703&imagename= Accessed: October 07, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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