Colonic adenocarcinoma metastases to the liver Colonic adenocarcinoma metastases to the liver. The tan-yellow nodules in the left and right lobes of this liver are metastases from a colonic adenocarcinoma. Metastasis as well as invasion is a definite indicator of a malignant neoplasm. The most common malignant neoplasm of the liver is a metastasis; however, the most common malignancy that metastasizes to the liver is a pulmonary neoplasm. Source: Chapter 4. Neoplasia, Pathology: The Big Picture Citation: Kemp WL, Burns DK, Brown TG. Pathology: The Big Picture; 2008 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/kemp1/kemp1_c004f009.png&sec=41568699&BookID=499&ChapterSecID=41568287&imagename= Accessed: October 07, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved