Barrett's esophagus: photodynamic therapy for ablation of dysplasia, reduction of specialized mucosa, and treatment of superficial esophageal cancer

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Presentation transcript:

Barrett's esophagus: photodynamic therapy for ablation of dysplasia, reduction of specialized mucosa, and treatment of superficial esophageal cancer Bergein F. Overholt, MD, Masoud Panjehpour, PhD Gastrointestinal Endoscopy Volume 42, Issue 1, Pages 64-70 (July 1995) DOI: 10.1016/S0016-5107(95)70246-6 Copyright © 1995 American Society for Gastrointestinal Endoscopy Terms and Conditions

Fig. 1 The 25 mm diameter, 3 cm windowed centering balloon used to deliver light during photodynamic therapy. The diffuser can be seen in the inner, centering tube within the balloon. Gastrointestinal Endoscopy 1995 42, 64-70DOI: (10.1016/S0016-5107(95)70246-6) Copyright © 1995 American Society for Gastrointestinal Endoscopy Terms and Conditions

Fig. 2 Results of photodynamic therapy of a superficial esophageal adenocarcinoma in a patient with Barrett's esophagus. A, 1.2 cm exophytic, T1 adenocarcinoma. B, Interstitial placement of light diffuser probe.C, Ulceration 1 month following PDT. D, site of cancer covered by squamous epithelium; biopsy result was negative for cancer. Gastrointestinal Endoscopy 1995 42, 64-70DOI: (10.1016/S0016-5107(95)70246-6) Copyright © 1995 American Society for Gastrointestinal Endoscopy Terms and Conditions

Fig. 2 Results of photodynamic therapy of a superficial esophageal adenocarcinoma in a patient with Barrett's esophagus. A, 1.2 cm exophytic, T1 adenocarcinoma. B, Interstitial placement of light diffuser probe.C, Ulceration 1 month following PDT. D, site of cancer covered by squamous epithelium; biopsy result was negative for cancer. Gastrointestinal Endoscopy 1995 42, 64-70DOI: (10.1016/S0016-5107(95)70246-6) Copyright © 1995 American Society for Gastrointestinal Endoscopy Terms and Conditions

Fig. 2 Results of photodynamic therapy of a superficial esophageal adenocarcinoma in a patient with Barrett's esophagus. A, 1.2 cm exophytic, T1 adenocarcinoma. B, Interstitial placement of light diffuser probe.C, Ulceration 1 month following PDT. D, site of cancer covered by squamous epithelium; biopsy result was negative for cancer. Gastrointestinal Endoscopy 1995 42, 64-70DOI: (10.1016/S0016-5107(95)70246-6) Copyright © 1995 American Society for Gastrointestinal Endoscopy Terms and Conditions

Fig. 2 Results of photodynamic therapy of a superficial esophageal adenocarcinoma in a patient with Barrett's esophagus. A, 1.2 cm exophytic, T1 adenocarcinoma. B, Interstitial placement of light diffuser probe.C, Ulceration 1 month following PDT. D, site of cancer covered by squamous epithelium; biopsy result was negative for cancer. Gastrointestinal Endoscopy 1995 42, 64-70DOI: (10.1016/S0016-5107(95)70246-6) Copyright © 1995 American Society for Gastrointestinal Endoscopy Terms and Conditions