Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Slides:



Advertisements
Similar presentations
Test practice Multiplication. Multiplication 9x2.
Advertisements

How to Manage High Risk Myeloma Dr Matthew Jenner Consultant Haematologist Southampton General Hospital UK Myeloma Forum Autumn Day 12 November 2014.
A Pilot Study of PLX3397, a Selective Colony-Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitor, in Pigmented Villonodular Synovitis (PVNS) Presented.
Support for pesticides playing a role in onset of multiple myeloma
Presented By Raymond Huang at 2014 ASCO Annual Meeting
CALGB/SWOG 80405: Phase III trial of FOLFIRI or FOLFOX with Bevacizumab or Cetuximab for patients w/ KRAS wild type untreated metastatic adenocarcinoma.
Geonomics in Breast Cancer Decoding Human Genome Luis Barreras, M.D., FACP.
Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS , ONO-4538) and ipilimumab (IPI) concurrent.
LESSON 4: PowerPoint slides to accompany Using Bioinformatics: Genetic Testing.
Translational Genomics Research Institute | The Sarcoma Data Portal: Making High Content Sarcoma Datasets Available For All Users Jonathan.
Early Reduction of Serum-Free Light Chains Associates with Renal Recovery in Myeloma Kidney Sophina Hissaund FY2.
A Randomized Phase 2 Trial Comparing Efficacy of the Combination of the PARP-inhibitor Olaparib and the Anti-angiogenic Cediranib Against Olaparib Alone.
Genes and Function: The Rewriting of our Textbooks of Pathology Presented By David Hafler at 2014 ASCO Annual Meeting.
Bevacizumab may Differentially Improve Survival for Patients with the Proliferative and Mesenchymal Molecular Subtype of Ovarian Cancer Presented By Boris.
Genetic Counseling Project Presented by: _________ Name of Disorder Is Ignorance a Bliss?
Presented By Fortunato Ciardiello at 2014 ASCO Annual Meeting
SATMathVideos.Net A set S consists of all multiples of 4. Which of the following sets are contained within set S? A) S2 only B) S4 only C) S2 and S4 D)
ASCO 2010 Lenalidomide maintenance after transplantation for myeloma (IFM Study) Authors: Attal et al, ASCO 2010 Abstract:
Slide 1 Presented By Pierre-Yves Dietrich at 2014 ASCO Annual Meeting.
Immediate vs. deferred initiation of androgen deprivation therapy in prostate cancer patients with PSA-only relapse. An observational follow-up study Presented.
Slide 1 Presented By Christian Hinrichs at 2014 ASCO Annual Meeting.
Slide 1 Presented By Jan Buckner at 2014 ASCO Annual Meeting.
A Prospective, Multicenter, Randomized Study of Anti-CCR4 Monoclonal Antibody Mogamulizumab (Moga) vs Investigator’s Choice (IC) in the Treatment of Patients.
Presented By Shin Fujita at 2016 ASCO Annual Meeting
Biomarkers for personalized therapy in myeloma
Overall Goal. Clinical Conversations: Nursing Care for Patients With Multiple Myeloma.
Controversies in multiple myeloma: Evidence-based update
Presented By Michele Cavo at 2016 ASCO Annual Meeting
Presented By Lorenz Trumper at 2016 ASCO Annual Meeting
Securing the cure in resectable lung cancer
Highlights: Myeloma Oral Session
Presented By Marco Colleoni at 2017 ASCO Annual Meeting
Presented By John Bartlett at 2017 ASCO Annual Meeting
continued on next slide
Presented By Jason Fangusaro at 2017 ASCO Annual Meeting
Presented By Amrita Krishnan at 2016 ASCO Annual Meeting
Sample Presentation. Slide 1 Info Slide 2 Info.
MRD in Myeloma: the Future is Here
                                                                                                                                                                                                                                                
continued on next slide
continued on next slide
Presented By James Rubenstein at 2016 ASCO Annual Meeting
Positioning NK-κB in multiple myeloma
Nat. Rev. Clin. Oncol. doi: /nrclinonc
Health Strategies Group
Accelerating drug discovery: Open source cancer cell biology?
HELLO THERE. THIS IS A TEST SLIDE SLIDE NUMBER 1.
Sumit Madan, MD, Robert A. Kyle, MD, Philip R. Greipp, MD 
Presented By Praful Ravi at 2016 ASCO Annual Meeting
Approaches in Newly Diagnosed Multiple Myeloma: When and What
Presented By Mathias Rummel at 2016 ASCO Annual Meeting
Figure 1 Translocations involved in multiple myeloma
Practical Guidance on the Management of Pan-Negative NSCLC
Revaccination after Autologous Hematopoietic Stem Cell Transplantation Is Safe and Effective in Patients with Multiple Myeloma Receiving Lenalidomide.
Communicating With Your Patients About Major Depressive Disorder
Cutaneous T-Cell Lymphoma: Disease, Diagnosis, and Therapy
Clinical Challenges in the Patient With Relapsed Multiple Myeloma
C.2.10 Sample Questions.
C.2.8 Sample Questions.
Baseline mutational patterns and sustained MRD negativity in patients with high-risk smoldering myeloma by Sham Mailankody, Dickran Kazandjian, Neha Korde,
Targeting Apoptosis in AML
C.2.8 Sample Questions.
Genome-Wide SNP Analysis in Cancer: Leukemia Shows the Way
continued on next slide
Presented By Joshua Richter at 2016 ASCO Annual Meeting
Importance of Early Diagnosis and Management in SMA
Presented By Andrew Evens at 2016 ASCO Annual Meeting
Increased frequency and number of KLL-specific clonotypes in tumors is associated with improved MCC-specific survival. Increased frequency and number of.
continued on next slide
A. B. C. D. Above median: Below median:
Presentation transcript:

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Genetic plasma cell signatures in high-risk smoldering myeloma versus multiple myeloma patients Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Massive genetic heterogeneity in <br />multiple myeloma Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Multiple myeloma consistently preceded by precursor states Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Slide 4 Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Slide 5 Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Patients and treatment response Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Samples and bioinformatic analysis Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Samples and bioinformatic analysis Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Slide 9 Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Slide 10 Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Significantly recurrent mutations in multiple myeloma Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Significantly recurrent mutations of individual genes in multiple myeloma Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Slide 13 Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Slide 14 Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Slide 15 Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Slide 16 Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Significantly recurrent mutations in multiple myeloma Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Recurrent mutations in the NF-kB pathway Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Number of patients with mutations in the NF-kB pathway genes Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Conclusions Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Conclusions (cont.) Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Myeloma Program at MSKCC Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Presented By Sham Mailankody at 2016 ASCO Annual Meeting Slide 23 Presented By Sham Mailankody at 2016 ASCO Annual Meeting

Thank you to our patients! Presented By Sham Mailankody at 2016 ASCO Annual Meeting