American Journal of Kidney Diseases

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American Journal of Kidney Diseases Effectiveness of Pharmacist Interventions on Cardiovascular Risk in Patients With CKD: A Subgroup Analysis of the Randomized Controlled RxEACH Trial Yazid N. Al Hamarneh, BSc(Pharm), PhD, Ross T. Tsuyuki, BSc(Pharm), PharmD, MSc, Charlotte A. Jones, MD, PhD, Braden Manns, MD, MSc, Marcello Tonelli, MD, PhD, Nairne Scott-Douglass, MD, PhD, Kailash Jindal, MD, Wendy Tink, MD, Brenda R. Hemmelgarn, MD, PhD American Journal of Kidney Diseases DOI: 10.1053/j.ajkd.2017.07.012 Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Study flow. Randomization refers to the original randomization in RxEACH (The Alberta Vascular Risk Reduction Community Pharmacy Project). More information about the number of the overall patients screened has been reported elsewhere.18 Abbreviation: CKD, chronic kidney disease. American Journal of Kidney Diseases DOI: (10.1053/j.ajkd.2017.07.012) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Primary outcome, the difference in change in estimated cardiovascular (CV) risk between the intervention and control groups at 3 months, found a relative risk reduction of 20% (absolute reduction, 5.03; 95% confidence interval, 3.4-6.65; P<0.001) in estimated CV risk over a 3-month period between the intervention and control groups, after adjusting for baseline values and the center effect. Vertical bars denote error bars. American Journal of Kidney Diseases DOI: (10.1053/j.ajkd.2017.07.012) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions