Apodemus agrarius is a potential natural host of severe fever with thrombocytopenia syndrome (SFTS)—causing novel bunyavirus Hongxia Ni, Fan Yang, Yongdong.

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Apodemus agrarius is a potential natural host of severe fever with thrombocytopenia syndrome (SFTS)—causing novel bunyavirus Hongxia Ni, Fan Yang, Yongdong Li, Wenbin Liu, Suli Jiao, Zixiong Li, Bo Yi, Yi Chen, Xiaomei Hou, Fengjiao Hu, Yibo Ding, Guolin Bian, Yan Du, Guozhang Xu, Guangwen Cao Journal of Clinical Virology Volume 71, Pages 82-88 (October 2015) DOI: 10.1016/j.jcv.2015.08.006 Copyright © 2015 Elsevier B.V. Terms and Conditions

Fig. 1 Temporal distribution of SFTS patients diagnosed in Ningbo, Zhejiang Province, China, between 2012 and 2014. Journal of Clinical Virology 2015 71, 82-88DOI: (10.1016/j.jcv.2015.08.006) Copyright © 2015 Elsevier B.V. Terms and Conditions

Fig. 2 Phylogenetic analyses of 13 SFTSV isolates in Zhejiang Provience, China and their reference sequences. A, the L segment; B, the M segment; C, the S segment. Circle symbol, isolates from patients in Dai-Shan, a neaby island; Square symbol, isolates from patients in rural Ningbo; triangle symbol, isolates from Apodemus agrarius in rural Ningbo. Journal of Clinical Virology 2015 71, 82-88DOI: (10.1016/j.jcv.2015.08.006) Copyright © 2015 Elsevier B.V. Terms and Conditions

Fig. 3 Cytopathic effect (CPE) of Vero cell cultures infected with SFTSV in the supernatants of homogenized lung tissues of Apodemus agrarius. A, normal Vero cells; B, CPE of Vero cell culture infected with Rodent01/NB/CHN/2014 on day 8; C, CPE of cell culture infected with the virus on day 11; D, CPE of cell culture infected with the virus on day 14. Journal of Clinical Virology 2015 71, 82-88DOI: (10.1016/j.jcv.2015.08.006) Copyright © 2015 Elsevier B.V. Terms and Conditions

Fig. 4 Hypothesis of SFTSV life cycle. Journal of Clinical Virology 2015 71, 82-88DOI: (10.1016/j.jcv.2015.08.006) Copyright © 2015 Elsevier B.V. Terms and Conditions

Journal of Clinical Virology 2015 71, 82-88DOI: (10. 1016/j. jcv. 2015 Copyright © 2015 Elsevier B.V. Terms and Conditions